Age and cancer incidence in 5.2 million people with HIV: the South African HIV Cancer Match study (Publications)
BACKGROUND: Old age is an important risk factor for developing cancer, but few data exist on this association in people with HIV (PWH) in sub-Saharan Africa. METHODS: The South African HIV Cancer Matc
Generation of aurachin derivatives by whole-cell biotransformation and evaluation of their antiprotozoal properties (Publications)
The natural product aurachin D is a farnesylated quinolone alkaloid, which is known to possess activity against the causative agent of malaria, Plasmodium spp. In this study, we show that aurachin D i
Diagnosis of helminths depends on worm fecundity and the distribution of parasites within hosts (Publications)
Helminth transmission and morbidity are dependent on the number of mature parasites within a host; however, observing adult worms is impossible for many natural infections. An outstanding challenge is
Modeling marine cargo traffic to identify countries in Africa with greatest risk of invasion by <em>Anopheles stephensi</em> (Publications)
Anopheles stephensi, an invasive malaria vector native to South Asia and the Arabian Peninsula, was detected in Djibouti's seaport, followed by Ethiopia, Sudan, Somalia, and Nigeria. If An. stephensi
How to scale-up: a comparative case study of scaling up a district health management strengthening intervention in Ghana, Malawi and Uganda (Publications)
BACKGROUND: The need to scale up public health interventions in low- and middle-income countries to ensure equitable and sustainable impact is widely acknowledged. However, there has been little under
The importance of the treatment rationale for pain in animal-assisted interventions: a randomized controlled trial in healthy participants (Publications)
Animal-assisted interventions (AAIs) is a promising treatment approach for pain, but possible mechanisms still need to be elucidated. This study set out to investigate the analgesic effects of an anim
Should we treat <em>Blastocystis </em>sp.? A double-blind placebo-controlled randomized pilot trial (Publications)
BACKGROUND: Blastocystis sp. is a worldwide-distributed protist colonizing the guts of humans and a great variety of animals. It is unclear whether it is just a commensal or an infectious parasite tha