Infected erythrocyte-derived extracellular vesicles alter vascular function via regulatory Ago2-miRNA complexes in malaria (Publications)
Malaria remains one of the greatest public health challenges worldwide, particularly in sub-Saharan Africa. The clinical outcome of individuals infected with Plasmodium falciparum parasites depends on
Ensuring transmission through dynamic host environments: host-pathogen interactions in <em>Plasmodium </em>sexual development (Publications)
A renewed global commitment to malaria elimination lends urgency to understanding the biology of Plasmodium transmission stages. Recent progress toward uncovering the mechanisms underlying Plasmodium
Sex: how malaria parasites get turned on (Publications)
The mechanisms underlying sexual stage switching in Plasmodium spp. have hitherto remained a mystery. However, two recent studies have revealed that an apicomplexan-specific DNA-binding protein is ess
An assay to probe <em>Plasmodium falciparum</em> growth, transmission stage formation and early gametocyte development (Publications)
Conversion from asexual proliferation to sexual differentiation initiates the production of the gametocyte, which is the malaria parasite stage required for human-to-mosquito transmission. This protoc
Effects of school-based physical activity and multi-micronutrient supplementation intervention on growth, health and well-being of schoolchildren in... (Publications)
BACKGROUND: In low- and middle-income countries, infectious diseases remain a key public health issue. Additionally, non-communicable diseases are a rapidly growing public health problem that impose a
Informed consent procedure in a double blind randomized anthelminthic trial on Pemba Island, Tanzania: do pamphlet and information session increase... (Publications)
BACKGROUND: In clinical research, obtaining informed consent from participants is an ethical and legal requirement. Conveying the information concerning the study can be done using multiple methods ye
Antibiotic exposure among children younger than 5 years in low-income and middle-income countries: a cross-sectional study of nationally... (Publications)
BACKGROUND: Antibiotic resistance is a major threat to global health. Although detailed information about antibiotic use in high-income countries is available, little is known regarding the use of ant
Dispersal of <em>Mycobacterium tuberculosis </em>driven by historical European trade in the South Pacific (Publications)
Mycobacterium tuberculosis (Mtb) is a globally distributed bacterial pathogen whose population structure has largely been shaped by the activities of its obligate human host. Oceania was the last majo
Structure, biosynthesis, and bioactivity of photoditritide from <em>Photorhabdus temperata</em> Meg1 (Publications)
A new cyclic peptide photoditritide (1), containing two rare amino acid d-homoarginine residues, was isolated from Photorhabdus temperata Meg1 after the nonribosomal peptide synthetase encoding gene p
Regulating pharmacists as contraception providers: a qualitative study from Coastal Kenya on injectable contraception provision to youth (Publications)
INTRODUCTION: Young people worldwide are often reticent to access family planning services from public health facilities: instead, they choose to get contraception from private, retail pharmacies. In
