A time-course comparative clinical and immune response evaluation study between the human pathogenic <em>Orientia tsutsugamushi </em>strains: Karp and... (Publications)
BACKGROUND: Scrub typhus is a vector-borne febrile illness caused by Orientia tsutsugamushi transmitted by the bite of Trombiculid mites. O. tsutsugamushi has a high genetic diversity and is increasin
What is ALMANACH? [Video] (Publications)
An electronic application is improving the quality of health care for children under five years old. ALMANACH, short for the Algorithm for the Management of Childhood Illness, is a user-friendly appli
Modelling the impact of Omicron and emerging variants on SARS-CoV-2 transmission and public health burden (Publications)
Background: SARS-CoV-2 variants of concern, such as Omicron (B.1.1.529), continue to emerge. Assessing the impact of their potential viral properties on the probability of future transmission dominanc
Interventions to reduce pesticide exposure from the agricultural sector in Africa: a workshop report (Publications)
Despite the fact that several cases of unsafe pesticide use among farmers in different parts of Africa have been documented, there is limited evidence regarding which specific interventions are effect
Relationships between long-term residential exposure to total environmental noise and stroke incidence (Publications)
Background: Noise has been related to several cardiovascular diseases (CVDs) such as coronary heart disease and to their risk factors such as hypertension, but associations with stroke remain under-re
Health systems resilience in practice: a scoping review to identify strategies for building resilience (Publications)
BACKGROUND: Research on health systems resilience has focused primarily on the theoretical development of the concept and its dimensions. There is an identified knowledge gap in the research on how to
Innovate to eliminate: a prerequisite in NTD programmes (Publications)
Innovation plays a critical role in progress towards achievement of the World Health Organization's road map for neglected tropical diseases 2021-2030. As disease prevalence decreases, the cost to ide
Community access to rectal artesunate for malaria (CARAMAL): a large-scale observational implementation study in the Democratic Republic of the Congo,... (Publications)
The key to reducing malaria deaths in highly endemic areas is prompt access to quality case management. Given that many severe cases occur at peripheral level, rectal artesunate (RAS) in the form of s
Using and improving the PHISICC paper-based tools in the health facility laboratories: examples of Human Centered Design taking systems thinking into... (Publications)
BackgroundHealth workers in low- and middle-income countries are increasingly demanded to collect more and more data to report them to higher levels of the health information system (HIS), in detrimen
Exploring a tetrahydroquinoline antimalarial hit from the medicines for malaria pathogen box and the identification of its mode of resistance as... (Publications)
New antimalarial treatments with novel mechanism of action are needed to tackle Plasmodium falciparum infections that are resistant to first-line therapeutics. Here we report the exploration of MMV692
