Assessing different next-generation sequencing technologies for wastewater-based epidemiology (Publications)
Wastewater-based epidemiology has proven to be an important public health asset during the COVID-19 pandemic. It can provide less biassed and more cost-effective population-level monitoring of the dis
Forecasting malaria dynamics based on causal relations between control interventions, climatic factors, and disease incidence in western Kenya (Publications)
BACKGROUND: Malaria remains one of the deadliest diseases worldwide, especially among young children in sub-Saharan Africa. Predictive models are necessary for effective planning and resource allocati
Respiratory and allergic outcomes among farmworkers exposed to pesticides in Costa Rica (Publications)
AIM: We examined the association of exposure to a pesticide mixture with respiratory and allergic outcomes among farmworkers from Costa Rica. METHODS: We conducted a cross-sectional study of 299 farmw
HIV co-infection increases the risk of post-tuberculosis mortality among persons who initiated treatment for drug-resistant tuberculosis (Publications)
Little is known regarding the relationship between common comorbidities in persons with tuberculosis (TB) (including human immunodeficiency virus [HIV], diabetes, and hepatitis C virus [HCV]) and post
Risk, attributable fraction and attributable number of cause-specific heat-related emergency hospital admissions in Switzerland (Publications)
OBJECTIVES: We assessed the relationship between heat and emergency hospital admissions (EHAs) in Switzerland using clinically relevant metrics. METHODS: Applying distributed lag non-linear models, we
Genotyping methods to distinguish <em>Plasmodium falciparum</em> recrudescence from new infection for the assessment of antimalarial drug efficacy: an... (Publications)
BACKGROUND: Distinguishing Plasmodium falciparum recrudescence from new infections is crucial for the assessment of antimalarial drug efficacy against P falciparum. We aimed to compare the efficacy of
The non-inferiority of piperonyl-butoxide Yorkool® G3 insecticide-treated nets compared to Olyset®Plus measured by <em>Anopheles arabiensis</em>... (Publications)
BACKGROUND: Non-inferiority trials are recommended by the World Health Organization (WHO) to demonstrate that health products show comparable efficacy to that of existing standard of care. As part of
Single-dose drug development candidate for schistosomiasis (Publications)
Aryl hydantoins were identified in the early 1980s as a promising antischistosomal chemotype. However, as exemplified by Ro 13-3978, this compound series produced antiandrogenic side effects on the ho