Longitudinal tracking and quantification of individual <em>Plasmodium falciparum </em>clones in complex infections (Publications)
Longitudinal tracking of individual Plasmodium falciparum strains in multi-clonal infections is essential for investigating infection dynamics of malaria. The traditional genotyping techniques did not
Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations (Publications)
Chronic obstructive pulmonary disease (COPD) is the leading cause of respiratory mortality worldwide. Genetic risk loci provide new insights into disease pathogenesis. We performed a genome-wide assoc
Subspecies typing of <em>Streptococcus agalactiae</em> based on ribosomal subunit protein mass variation by MADLI-TOF MS (Publications)
Background: A ribosomal subunit protein (rsp)-based matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) method was developed for fast subspecies-level typing of
Multistage antiplasmodium activity of astemizole analogues and inhibition of hemozoin formation as a contributor to their mode of action (Publications)
A drug repositioning approach was leveraged to derivatize astemizole (AST), an antihistamine drug whose antimalarial activity was previously identified in a high-throughput screen. The multistage acti
