The W-Beijing lineage of <em>Mycobacterium tuberculosis</em> overproduces triglycerides and has the DosR dormancy regulon constitutively upregulated (Publications)
The Beijing family of Mycobacterium tuberculosis strains has been associated with epidemic spread and an increased likelihood of developing drug resistance. The characteristics that predispose this fa
An algorithm for the clinical differentiation of malaria and typhoid: a preliminary communication (Publications)
The objective of this study was to determine which clinical features of typhoid and malaria are most helpful in distinguishing the two diseases among Papua New Guinean highlanders. In a study of 35 pa
Leishmanicidal activity of new megazol derivatives (Publications)
A series of thirteen new megazol derivatives, designed exploring the molecular hybridization approach between megazol (3) and heterocombretastatins (2), was synthesized. These new compounds were teste
Evaluation of street facilities I, II and III in Basel (Publications)
In June 1991 the city of Basel established the first low threshold centre (LTC) subsidized by the government after various private initiatives of "Live & Survive" aids. This low threshold facility whi
Methods development for epidemiologic investigations of the health effects of prolonged ozone exposure. Part II. An approach to retrospective... (Publications)
An extensive body of data supports a relation between acute exposures to ambient ozone and the occurrence of various acute respiratory symptoms and changes in measures of lung function. In contrast, r
Diaryl sulfide-based inhibitors of trypanothione reductase: inhibition potency, revised binding mode and antiprotozoal activities (Publications)
Trypanothione reductase (TR) is an essential enzyme of trypanosomatids and therefore a promising target for the development of new drugs against African sleeping sickness and Chagas' disease. Diaryl s