Macrophage susceptibility to infection by Ghanaian <em>Mycobacterium tuberculosis</em> complex lineages 4 and 5 varies with self-reported ethnicity (Publications)
BACKGROUND: The epidemiology of Mycobacterium tuberculosis complex (MTBC) lineage 5 (L5) infections in Ghana revealed a significantly increased prevalence in Ewes compared to other self-reported ethni
Testing and treatment for malaria elimination: a systematic review (Publications)
BACKGROUND: Global interest in malaria elimination has prompted research on active test and treat (TaT) strategies. METHODS: A systematic review and meta-analysis were conducted to assess the effectiv
Risk of imported malaria infections in Zanzibar: a cross-sectional study (Publications)
BACKGROUND: Zanzibar has made substantial progress in malaria control with vector control, improved diagnosis, and artemisinin-based combination therapy. Parasite prevalence in the population has rema
Guillain-Barré syndrome associated with hepatitis E virus infection: a case report (Publications)
KEY CLINICAL MESSAGE: Hepatitis E virus (HEV) infection can be manifested with several neurological syndromes including GBS. Therefore, healthcare providers should consider HEV in their differential d
Whole-genome sequencing for One Health surveillance of antimicrobial resistance in conflict zones: a case study of <em>Salmonella</em> spp. and... (Publications)
Antimicrobial resistance (AMR) is a critical global concern driven by the overuse, misuse, and/or usage of inadequate antibiotics on humans, animals' agriculture, and as a result of contaminated envir
Health system performance and resilience in times of crisis: an adapted conceptual framework (Publications)
With the COVID-19 pandemic, the notion of health system (HS) performance has been discussed, and the notion of resilience has become increasingly important. Lacking a recognised framework that measure
Efficacy of the spatial repellent product Mosquito Shield™ against wild pyrethroid-resistant <em>Anopheles arabiensis</em> in south-eastern Tanzania (Publications)
BACKGROUND: Spatial repellents that create airborne concentrations of an active ingredient (AI) within a space offer a scalable solution to further reduce transmission of malaria, by disrupting mosqui
Effect of compensatory evolution in the emergence and transmission of rifampicin-resistant <em>Mycobacterium tuberculosis </em>in Cape Town, South... (Publications)
BACKGROUND: Experimental data show that drug-resistance-conferring mutations are often associated with a decrease in the replicative fitness of bacteria in vitro, and that this fitness cost can be mit
Association of long-term exposure to ambient air pollution with retinal neurodegeneration: the prospective Alienor study (Publications)
Chronic exposure to air pollution may have adverse effects on neurodegenerative diseases. Glaucoma, the second leading cause of blindness worldwide, is a neurodegenerative disease of the optic nerve,
Intestinal helminth infections and associated risk factors among adults in the Lao People's Democratic Republic (Publications)
BACKGROUND: Helminthiases are highly endemic in Southeast Asia, including the Lao People's Democratic Republic (Lao PDR). This study aimed to assess the current intestinal helminth infections and the