Urogenital schistosomiasis transmission on Unguja Island, Zanzibar: characterisation of persistent hot-spots (Publications)
BACKGROUND: Elimination of urogenital schistosomiasis transmission is a priority for the Zanzibar Ministry of Health. Preventative chemotherapy together with additional control interventions have succ
Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis... (Publications)
BACKGROUND: Non-fatal outcomes of disease and injury increasingly detract from the ability of the world's population to live in full health, a trend largely attributable to an epidemiological transiti
Re-infection with <em>Fasciola gigantica</em> 6-months post-treatment with triclabendazole in cattle from mobile pastoralist husbandry systems at Lake... (Publications)
At Lake Chad in central Africa, livestock fascioliasis caused by Fasciola gigantica represents a major veterinary health problem, particularly in cattle reared in mobile pastoralist husbandry systems.
Synthesis, DNA binding and antitrypanosomal activity of benzimidazole analogues of DAPI (Publications)
A series of novel benzimidazole diamidines were prepared from the corresponding dicyano analogues either by applying Pinner methodology (5a-c, 10 and 13a) or by making amidoximes intermediates that we
The burden of leprosy in Cameroon: fifteen years into the post-elimination era (Publications)
BACKGROUND: Cameroon achieved the elimination target of leprosy in 2000, and has maintained this status ever since. However, a number of health districts in the country continue to report significant
2-Octadecynoic acid as a dual life stage inhibitor of <em>Plasmodium</em> infections and plasmodial FAS-II enzymes (Publications)
The malaria parasite Plasmodium goes through two life stages in the human host, a non-symptomatic liver stage (LS) followed by a blood stage with all clinical manifestation of the disease. In this stu
Examples of coupled human and environmental systems from the extractive industry and hydropower sector interfaces (Publications)
Large-scale corporate projects, particularly those in extractive industries or hydropower development, have a history from early in the twentieth century of creating negative environmental, social, an
Costs and cost-effectiveness of <em>Plasmodium vivax </em>control (Publications)
The continued success of efforts to reduce the global malaria burden will require sustained funding for interventions specifically targeting Plasmodium vivax The optimal use of limited financial resou