SESOTHO trial ("Switch Either near Suppression Or THOusand") - switch to second-line versus WHO-guided standard of care for unsuppressed patients on... (Publications)
second-line ART in patients with sustained unsuppressed VL. METHODS: In this multicenter, parallel-group, open-label, randomized controlled trial conducted in Lesotho, patients on first-line ART with two consecutive
Software application profile: opal and mica: open-source software solutions for epidemiological data management, harmonization and dissemination (Publications)
improvements in health. To address this, Maelstrom Research proposes Opal and Mica, two inter-operable open-source software packages providing out-of-the-box solutions for epidemiological data management, [...] conducting more complex federated analyses involving statistical models. Availability: Opal and Mica are open-source and freely available at [ www.obiba.org ] under a General Public License (GPL) version 3, and
Differences between outdoor and indoor sound levels for open, tilted, and closed windows (Publications)
median outdoor-indoor sound level differences were of 10 dB(A) for open, 16 dB(A) for tilted, and 28 dB(A) for closed windows. For open and tilted windows, the most relevant parameters affecting the ou [...] recordings were performed outdoors and indoors, in the living room and in the bedroom. Three scenarios-of open, tilted, and closed windows-were recorded for three minutes each. For each situation, data on additional
Efficacy and safety of mefloquine, artesunate, mefloquine-artesunate, tribendimidine, and praziquantel in patients with <em>Opisthorchis... (Publications)
compared with that of praziquantel in patients with O viverrini infection. METHODS: We did a randomised open-label trial between February and April, 2010, in the Saysetha district, Attapeu Province, Laos. Eligible
A prospective, open-label, randomized trial of doxycycline versus azithromycin for the treatment of uncomplicated murine typhus (Publications)
evidence for optimum treatment duration. Azithromycin is a potential alternative. Methods: A prospective, open, randomised trial was conducted in non-pregnant, consenting inpatient adults with rapid diagnostic
SMSs as an alternative to provider-delivered care for unhealthy alcohol use: study protocol for <em>Leseli</em>, an open-label randomised controlled... (Publications)
use (as detailed by the primary and secondary outcomes below). METHODS: This is a two-arm randomised open-label multicentre superiority trial. Participants allocated to mhGAP-Standard receive 4 in-person
The impact of home-installed growth charts and small-quantity lipid-based nutrient supplements (SQ-LNS) on child growth in Zambia: a four-arm parallel... (Publications)
BACKGROUND: Childhood stunting remains common in many low-income settings and is associated with increased morbidity and mortality, as well as impaired child development. METHODS: The main objective o
Resistance-informed versus empirical management of viraemia in children and adolescents with HIV in Lesotho and Tanzania (GIVE MOVE trial): a... (Publications)
little access to GRT. METHODS: The Genotype-Informed Versus Empirical Management of Viremia (GIVE MOVE) open-label, parallel-group randomised controlled trial enrolled children and adolescents with HIV between
Feasibility and acceptability of the Problem Management for Moms programme for improving maternal mental health in Zambia: an open-label trial (Publications)
adapted psychosocial intervention for distressed mothers in low-resource settings. METHODS: In this open-label trial, we enrolled women living in Lusaka, Zambia, with high mental distress (> 7 score on the