Modelling the epidemiological impact of intermittent preventive treatment against malaria in infants (Publications)
BACKGROUND: Trials of intermittent preventive treatment against malaria in infants (IPTi) using sulphadoxine-pyrimethamine (SP) have shown a positive, albeit variable, protective efficacy against clin
The unmet need for emergency obstetric care in Tanga Region, Tanzania (Publications)
ABSTRACT: BACKGROUND: Improving maternal health by reducing maternal mortality constitutes the fifth Millennium Development Goal and represents a key public health challenge in the United Republic of
Isolation of <em>Trypanosoma brucei gambiense</em> from cured and relapsed sleeping sickness patients and adaptation to laboratory mice (Publications)
BACKGROUND: Sleeping sickness due to Trypanosoma brucei (T.b.) gambiense is still a major public health problem in some central African countries. Historically, relapse rates around 5% have been obser
In-hospital safety in field conditions of nifurtimox eflornithine combination therapy (NECT) for <em>T.b. gambiense</em> sleeping sickness (Publications)
BACKGROUND: Trypanosoma brucei (T.b.) gambiense Human African trypanosomiasis (HAT; sleeping sickness) is a fatal disease. Until 2009, available treatments for 2(nd) stage HAT were complicated to use,
Phylogenomics of ligand-gated ion channels predicts monepantel effect (Publications)
The recently launched veterinary anthelmintic drench for sheep (Novartis Animal Health Inc., Switzerland) containing the nematocide monepantel represents a new class of anthelmintics: the amino-aceton
