Point-of-care ultrasound: a useful diagnostic tool in Africa (Publications)
In resource limited settings with limited tests and diagnostic tools, most of diagnoses are based on clinical findings, and patients are managed empirically, e.g. with anti-tuberculosis drugs. This ar
Whole genome sequencing and spatial analysis identifies recent tuberculosis transmission hotspots in Ghana (Publications)
Whole genome sequencing (WGS) is progressively being used to investigate the transmission dynamics of Mycobacterium tuberculosis complex (MTBC). We used WGS analysis to resolve traditional genotype cl
The epidemiology of <em>Plasmodium falciparum </em>and <em>Plasmodium vivax</em> in East Sepik Province, Papua New Guinea, pre- and... (Publications)
BACKGROUND: In the past decade, national malaria control efforts in Papua New Guinea (PNG) have received renewed support, facilitating nationwide distribution of free long-lasting insecticidal nets (L
Developing an SMS text message intervention on sexual and reproductive health with adolescents and youth in Peru (Publications)
BACKGROUND: Improved access to sexual and reproductive health (SRH) services and information is essential for supporting adolescents and youth in making informed decisions and optimizing each young pe
The global progress of soil-transmitted helminthiases control in 2020 and World Health Organization targets for 2030 (Publications)
Soil-transmitted helminth (STH) infections are the most widespread of the neglected tropical diseases, primarily affecting marginalized populations in low- and middle-income countries. More than one b
Clinical data combined with modelling and simulation indicate unchanged drug-drug interaction magnitudes in the elderly (Publications)
Age-related comorbidities and consequently polypharmacy are highly prevalent in the elderly, resulting in an increased risk for drug-drug interactions (DDIs). The effect of aging on DDI magnitudes is
Abbreviated and comprehensive literature searches led to identical or very similar effect estimates: meta-epidemiological study (Publications)
OBJECTIVE: Assessing the agreement of treatment effect estimates from meta-analyses based on abbreviated or comprehensive literature searches. STUDY DESIGN AND SETTING: Meta-epidemiological study. We
A modular framework for the development of targeted Covid-19 blood transcript profiling panels (Publications)
BACKGROUND: Covid-19 morbidity and mortality are associated with a dysregulated immune response. Tools are needed to enhance existing immune profiling capabilities in affected patients. Here we aimed
Semi-field evaluation of freestanding transfluthrin passive emanators and the BG sentinel trap as a "push-pull control strategy" against <em>Aedes... (Publications)
BACKGROUND: Spatial repellents that drive mosquitoes away from treated areas, and odour-baited traps, that attract and kill mosquitoes, can be combined and work synergistically in a push-pull system.
Does resistance to pyrazinamide accurately indicate the presence of <em>Mycobacterium bovis</em>? (Publications)
Mycobacterium bovis is best identified by screening those isolates of the Mycobacterium tuberculosis complex that have any pyrazinamide (PZA) resistance, using a confirmatory test such as spoligotypin