How much remains undetected? Probability of molecular detection of human <em>Plasmodia</em> in the field (Publications)
BACKGROUND: In malaria endemic areas, most people are simultaneously infected with different parasite clones. Detection of individual clones is hampered when their densities fluctuate around the detec
Modern geographical reconnaissance of target populations in malaria elimination zones (Publications)
ABSTRACT: BACKGROUND: Geographical Reconnaissance (GR) operations using Personal Digital Assistants (PDAs) and Global Positioning Systems (GPS) have been conducted in the elimination provinces of Temo
Routine delivery of artemisinin-based combination treatment at fixed health facilities reduces malaria prevalence in Tanzania: an observational study (Publications)
ABSTRACT: BACKGROUND: Artemisinin-based combination therapy (ACT) has been promoted as a means to reduce malaria transmission due to their ability to kill both asexual blood stages of malaria parasite
Adenosine kinase of <em>T. b. Rhodesiense</em> identified as the putative target of 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine using chemical... (Publications)
BACKGROUND: Human African trypanosomiasis (HAT), a major parasitic disease spread in Africa, urgently needs novel targets and new efficacious chemotherapeutic agents. Recently, we discovered that 4-[5
Efficacy and safety of artemether in the treatment of chronic fascioliasis in Egypt: exploratory phase-2 trials (Publications)
BACKGROUND: Fascioliasis is an emerging zoonotic disease of considerable veterinary and public health importance. Triclabendazole is the only available drug for treatment. Laboratory studies have docu
Sequence conservation in <em>Plasmodium falciparum</em> á-helical coiled coil domains proposed for vaccine development (Publications)
BACKGROUND: The availability of the P. falciparum genome has led to novel ways to identify potential vaccine candidates. A new approach for antigen discovery based on the bioinformatic selection of he
An approach to addressing governance from a health system framework perspective (Publications)
ABSTRACT: As countries strive to strengthen their health systems in resource constrained contexts, policy makers need to know how best to improve the performance of their health systems. To aid these
Invasive snails and an emerging infectious disease: results from the first national survey on <em>Angiostrongylus cantonensis</em> in China (Publications)
BACKGROUND: Eosinophilic meningitis (angiostrongyliasis) caused by Angiostrongylus cantonensis is emerging in mainland China. However, the distribution of A. cantonensis and its intermediate host snai
