Artemether-lumefantrine treatment of uncomplicated <em>Plasmodium falciparum</em> malaria: a systematic review and meta-analysis of day 7 lumefantrine... (Publications)
BACKGROUND: Achieving adequate antimalarial drug exposure is essential for curing malaria. Day 7 blood or plasma lumefantrine concentrations provide a simple measure of drug exposure that correlates w
Building-related health impacts in European and Chinese cities: a scalable assessment method (Publications)
BACKGROUND: Public health is often affected by societal decisions that are not primarily about health. Climate change mitigation requires intensive actions to minimise greenhouse gas emissions in the
Assessment of parental perception of malaria vaccine in Tanzania (Publications)
BACKGROUND: Clinical trials of the RTS,S malaria vaccine have completed Phase III and the vaccine is on track for registration. Before making decisions about implementation, it is essential to prepare
Spatial and temporal variation of malaria entomological parameters at the onset of a hydro-agricultural development in central Côte d'Ivoire (Publications)
BACKGROUND: A deeper understanding of the ecology and small-scale heterogeneity of malaria transmission is essential for the design of effective prevention, control and elimination interventions. The
Financial and economic costs of the elimination and eradication of onchocerciasis (river blindness) in Africa (Publications)
BACKGROUND: Onchocerciasis (river blindness) is a parasitic disease transmitted by blackflies. Symptoms include severe itching, skin lesions, and vision impairment including blindness. More than 99% o
Feasibility and acceptability of injectable artesunate for the treatment of severe malaria in the Democratic Republic of Congo (Publications)
BACKGROUND: The Democratic Republic of the Congo (DRC) changed its national policy for the treatment of severe malaria in both children and adults in 2012 from intravenous quinine to injectable artesu
Clinical determinants of early parasitological response to ACTs in African patients with uncomplicated falciparum malaria: a literature review and... (Publications)
BACKGROUND: Artemisinin-resistant Plasmodium falciparum has emerged in the Greater Mekong sub-region and poses a major global public health threat. Slow parasite clearance is a key clinical manifestat
Do instructional videos on sputum submission result in increased tuberculosis case detection? A randomized controlled trial (Publications)
OBJECTIVE: We examined the effect of an instructional video about the production of diagnostic sputum on case detection of tuberculosis (TB), and evaluated the acceptance of the video. TRIAL DESIGN: R
Functional analysis and transcriptional output of the Göttingen minipig genome (Publications)
BACKGROUND: In the past decade the Göttingen minipig has gained increasing recognition as animal model in pharmaceutical and safety research because it recapitulates many aspects of human physiology a