Generation of chimeric monoclonal antibodies from mice that carry human immunoglobulin Cgamma1 heavy of Ckappa light chain gene segments (Publications)
Gene targeting in mouse embryonic stem (ES) cells was used to replace (i) the mouse immunoglobulin heavy chain (IgH) Cgamma2a gene segment (mCgamma2a) with the human Cgamma1 gene segment (hCgamma1), a
<em>Plasmodium falciparum</em> protein kinase 5 and the malarial nuclear division cycles (Publications)
In the course of our studies on cell cycle regulation mechanisms of Plasmodium falciparum, we investigated expression pattern, kinase activity, and localization of PfPK5, a putative malarial member of
Psychiatric disorders, suicidality, and personality among young men by sexual orientation (Publications)
Personality and its potential role in mediating risk of psychiatric disorders and suicidality are assessed by sexual orientation, using data collected among young Swiss men (n=5875) recruited while pr
Heterochromatin protein 1 secures survival and transmission of malaria parasites (Publications)
Clonally variant expression of surface antigens allows the malaria parasite Plasmodium falciparum to evade immune recognition during blood stage infection and secure malaria transmission. We demonstra
Nitrogen dioxide and mortality: review and meta-analysis of long-term studies (Publications)
Exposure to ambient nitrogen dioxide (NO2) has been linked to increased mortality in several epidemiological studies but the question remains of whether NO2 is directly responsible for the health effe
Feeding behaviour of tsetse flies infected with <em>salivarian trypanosomes</em> (Publications)
Although much is known about factors which determine infection rates of salivarian trypanosomes (subgenera Nannomonas, Duttonella and Tryanozoon) in the tsetse fly Glossina, it is not clear why infect
<em>In vitro</em> and <em>in vivo</em> activity of the chloroaryl-substituted imidazole viniconazole against <em>Trypanosoma cruzi</em> (Publications)
Chagas disease (CD) is caused by the intracellular protozoan parasite Trypanosoma cruzi and affects more than 10 million people in poor areas of Latin America. There is an urgent need for alternative