Antiprotozoal activities of organic extracts from French marine seaweeds (Publications)
Marine macrophytes contain a variety of biologically active compounds, some reported to have antiprotozoal activity in vitro. As a part of a screening program to search for new natural antiprotozoals,
Inhibitory activity of marine sponge-derived natural products against parasitic protozoa (Publications)
In this study, thirteen sponge-derived terpenoids, including five linear furanoterpenes: furospinulosin-1 (1), furospinulosin-2 (2), furospongin-1 (3), furospongin-4 (4), and demethylfurospongin-4 (5)
The use of mobile phones for demographic surveillance of mobile pastoralists and their animals in Chad: proof of principle (Publications)
BACKGROUND: Demographic information is foundational for the planning and management of social programmes, in particular health services. The existing INDEPTH network surveillance sites are limited to
Uptake of guidelines on prevention of mother-to-child transmission of HIV in rural Tanzania: time for change (Publications)
Guidelines on prevention of mother-to-child transmission (PMTCT) of human immunodeficiency virus (HIV) are inconsistently implemented in low-income countries. Strategies are needed to improve the upta
Comparative genomics reveals multiple genetic backgrounds of human pathogenicity in the <em>Trypanosoma brucei</em> complex (Publications)
The Trypanosoma brucei complex contains a number of subspecies with exceptionally variable life histories, including zoonotic subspecies, which are causative agents of human African trypanosomiasis (H
High prevalence of <em>Ancylostoma ceylanicum</em> hookworm infections in humans, Cambodia, 2012 (Publications)
Ancylostoma ceylanicum, a hookworm of canids and felids in Asia, is becoming the second most common hookworm infecting humans. In 2012, we investigated the prevalence and infection dynamics of and ris
Risk stratification for 1-year mortality in acute heart failure: classification and regression tree analysis (Publications)
BACKGROUND: Simple tools for risk stratification of patients with acute heart failure (AHF) are an unmet clinical need, particularly regarding long-term mortality. METHODS: We prospectively enrolled 6
1,2-substituted 4-(1H)-quinolones: synthesis, antimalarial and antitrypanosomal activities in vitro (Publications)
A diverse array of 4-(1H)-quinolone derivatives bearing substituents at positions 1 and 2 were synthesized and evaluated for antiprotozoal activities against Plasmodium falciparum and Trypanosoma bruc
Mycobacterial lineages causing pulmonary and extrapulmonary tuberculosis, Ethiopia (Publications)
Molecular typing of 964 specimens from patients in Ethiopia with lymph node or pulmonary tuberculosis showed a similar distribution of Mycobacterium tuberculosis strains between the 2 disease manifest
Assessment of dual life stage antiplasmodial activity of British seaweeds (Publications)
Terrestrial plants have proven to be a prolific producer of clinically effective antimalarial drugs, but the antimalarial potential of seaweeds has been little explored. The main aim of this study was
