Self-nanoemulsifying drug-delivery systems improve oral absorption and antischistosomal activity of epiisopiloturine (Publications)
AIM: To develop a self-nanoemulsifying drug-delivery system (SNEDDS) able to improve oral absorption of epiisopiloturine (EPI), and test the antischistosomal activity in a mice model. RESULTS: SNEDDS
Mbandakamine-type naphthylisoquinoline dimers and related alkaloids from the central African liana <em>ancistrocladus ealaensis </em>with... (Publications)
Four new dimeric naphthylisoquinoline alkaloids, michellamine A5 (2) and mbandakamines C-E (4-6), were isolated from the Congolese plant Ancistrocladus ealaensis, along with the known dimer mbandakami
A multi-country analysis on potential adaptive mechanisms to cold and heat in a changing climate (Publications)
BACKGROUND: Temporal variation of temperature-health associations depends on the combination of two pathways: pure adaptation to increasingly warmer temperatures due to climate change, and other atten
Retrospective active case finding in Cambodia: an innovative approach to leprosy control in a low-endemic country (Publications)
Currently, leprosy control relies on the clinical diagnosis of leprosy and the subsequent administration of multidrug therapy (MDT). However, many health workers are not familiar with the cardinal sig
Impact and cost-effectiveness of snail control to achieve disease control targets for schistosomiasis (Publications)
Schistosomiasis is a parasitic disease that affects over 240 million people globally. To improve population-level disease control, there is growing interest in adding chemical-based snail control inte
Microbiological airway colonization in COPD patients with severe emphysema undergoing endoscopic lung volume reduction (Publications)
Background: Endoscopic lung volume reduction (eLVR) is a therapeutic option for selected patients with COPD and severe emphysema. Infectious exacerbations are serious events in these vulnerable patien
Time trends of positivity rates from foodborne pathogen testing in Switzerland, 2003 to 2012 (Publications)
BACKGROUND: Campylobacteriosis and salmonellosis are important foodborne diseases in Europe, including in Switzerland. In 2014, notification rates for Switzerland were 92.9 per 100 000 population for
Time to change focus? Transitioning from higher neonatal to higher stillbirth mortality in São Paulo State, Brazil (Publications)
BACKGROUND: Differential trends in mortality suggest that stillbirths may dominate neonatal mortality in the medium to long run. Brazil has made major efforts to improve data collection on health indi
