Single-dose hepatitis A immunization: 7.5-year observational pilot study in Nicaraguan children to assess protective effectiveness and humoral immune... (Publications)
BACKGROUND: Universal 2-dose hepatitis A virus (HAV) vaccination of toddlers effectively controls hepatitis A. High vaccine costs, however, impede implementation in endemic countries. To test single-d
Childhood vaccination communication outcomes unpacked and organised in a taxonomy to facilitate core outcome establishment (Publications)
OBJECTIVE: We present a comprehensive taxonomy of outcomes for childhood vaccination communication interventions. Adding to our earlier map of trial outcomes, we aimed to: 1) identify relevant outcome
Metabolic syndrome in patients on first-line antiretroviral therapy containing zidovudine or tenofovir in rural Lesotho, Southern Africa (Publications)
OBJECTIVE: To assess the prevalence of metabolic syndrome (MetS) among patients in rural Lesotho who are taking first-line anti-retroviral therapy (ART) containing either zidovudine or tenofovir disop
Antimicrobial resistance in <em>Mycobacterium tuberculosis</em>: mechanistic and evolutionary perspectives (Publications)
Antibiotic-resistant Mycobacterium tuberculosis strains are threatening progress in containing the global tuberculosis epidemic. Mycobacterium tuberculosis is intrinsically resistant to many antibioti
Father's environment before conception and asthma risk in his children: a multi-generation analysis of the Respiratory Health In Northern Europe... (Publications)
BACKGROUND: Whereas it is generally accepted that maternal environment plays a key role in child health, emerging evidence suggests that paternal environment before conception also impacts child healt
An evaluation of minor groove binders as anti-fungal and anti-mycobacterial therapeutics (Publications)
This study details the synthesis and biological evaluation of a collection of 19 structurally related Minor Groove Binders (MGBs), derived from the natural product distamycin, which were designed to p