Quantitative assessment of eosinophiluria in <em>Schistosoma haematobium</em> infections: a new marker of infection and bladder morbidity (Publications)
Eosinophiluria, as quantified by measuring eosinophil cationic protein (ECP) in urinary extracts, microhematuria, egg excretion, and ultrasound-detectable bladder pathology were recorded in Schistosom
Meat preparation and colorectal adenomas in a large sigmoidoscopy-based case-control study in California (United States) (Publications)
The often observed association between red meat and colorectal cancer could be due in part to mutagens, such as heterocyclic amines (HCA), that are present in cooked meat. HCAs are highly mutagenic an
Synthesis and antitrypanosomal evaluation of derivatives of N-benzyl-1,2-dihydroquinolin-6-ols: effect of core substitutions and salt formation (Publications)
Analogs of the trypanocidal lead compound 1-benzyl-1,2-dihydro-2,2,4-trimethylquinolin-6-yl acetate were prepared to extend the structure-activity relationship in this series of molecules, improve the
A Bayesian approach to estimate the age-specific prevalence of <em>Schistosoma mansoni</em> and implications for schistosomiasis control (Publications)
Models that accurately estimate the age-specific infection prevalence of Schistosoma mansoni can be useful for schistosomiasis control programmes, particularly with regard to whether mass drug adminis
Validity of annoyance scores for estimation of long term air pollution exposure in epidemiologic studies: the Swiss Study on Air Pollution and Lung... (Publications)
In air pollution epidemiology, estimates of long term exposure are often based on measurements made at one fixed site monitor per area. This may lead to exposure misclassification. The present paper v
A novel in vitro screening assay for trypanocidal activity using the fluorescent dye BCECF-AM (Publications)
A cell viability assay, using fluorescence measurements has been developed for the screening of new compounds against African trypanosomes. 2',7'-Bis-(carboxyethyl)-5(6)-carboxyfluorescein-pentaacetox
Use of B-type natriuretic peptide in the management of hypoxaemic respiratory failure (Publications)
AIMS: Evaluation and management of patients with hypoxaemic respiratory failure in the intensive care unit (ICU) are difficult. The use of B-type natriuretic peptide (BNP), a quantitative marker of ca
Activity and structure relationship of acridine derivatives against African trypanosomes (Publications)
48 newly synthesized acridine derivatives of different classes were screened for antitrypanosomal activity. They showed a dose dependent effect on Trypanosoma rhodesiense and T. brucei bloodstream for