Public health impact and cost-effectiveness of the RTS,S/AS01 malaria vaccine: a systematic comparison of predictions from four mathematical models (Publications)
BACKGROUND: The phase 3 trial of the RTS,S/AS01 malaria vaccine candidate showed modest efficacy of the vaccine against Plasmodium falciparum malaria, but was not powered to assess mortality endpoints
Home-based and facility-based directly observed therapy of tuberculosis treatment under programmatic conditions in urban Tanzania (Publications)
INTRODUCTION: Decentralization of Directly Observed Treatment (DOT) for tuberculosis (TB) to the community (home-based DOT) has improved the coverage of TB treatment and reduced the burden to the heal
Spatiotemporal co-existence of two <em>Mycobacterium ulcerans</em> clonal complexes in the Offin River valley of Ghana (Publications)
In recent years, comparative genome sequence analysis of African Mycobacterium ulcerans strains isolated from Buruli ulcer (BU) lesion specimen has revealed a very limited genetic diversity of closely
Assessing stool quantities generated by three specific Kato-Katz thick smear templates employed in different settings (Publications)
BACKGROUND: The Kato-Katz technique is recommended for the diagnosis of helminth infections in epidemiological surveys, drug efficacy studies and monitoring of control interventions. We assessed the c
Measuring the health-related Sustainable Development Goals in 188 countries: a baseline analysis from the Global Burden of Disease Study 2015 (Publications)
BACKGROUND: In September, 2015, the UN General Assembly established the Sustainable Development Goals (SDGs). The SDGs specify 17 universal goals, 169 targets, and 230 indicators leading up to 2030. W
Within host evolution selects for a dominant genotype of <em>Mycobacterium tuberculosis</em> while T cells increase pathogen genetic diversity (Publications)
Molecular epidemiological assessments, drug treatment optimization, and development of immunological interventions all depend on understanding pathogen adaptation and genetic variation, which differ f
Incidence and types of adverse events during mass vaccination campaign with the meningococcal A conjugate vaccine (MENAFRIVACTM) in Cameroon (Publications)
PURPOSE: A new vaccine against meningitis A was introduced in Africa meningitis belt in 2010. This study was planned to describe the incidence and types of adverse events following immunization (AEFIs
