Antiprotozoal activities of tetrazole-quinolines with aminopiperidine linker (Publications)
BACKGROUND: Human African Trypanosomiasis (HAT, sleeping sickness) and Malaria both are insect vectored tropical diseases. Only a couple of drugs is able to cure HAT, but all of them are toxic, prone
Integrating standardized whole genome sequence analysis with a global <em>Mycobacterium tuberculosis</em> antibiotic resistance knowledgebase (Publications)
Drug-resistant tuberculosis poses a persistent public health threat. The ReSeqTB platform is a collaborative, curated knowledgebase, designed to standardize and aggregate global Mycobacterium tubercul
<em>In vitro</em> and<em> in vivo</em> drug-drug interaction study of the effects of ivermectin and oxantel pamoate on tribendimidine (Publications)
Soil-transmitted helminth (STH) infections still remain a major health problem in poor rural settings. The lack of efficacious drugs against all STH species raises the interest in drug combinations. D
Does the DOSPERT scale predict risk taking behaviour during travel? A study using smartphones (Publications)
Background: Despite the continuing growth of international tourism, very little research has been done on the link between individual risk attitudes and health behaviours during travel. Our study uses
C-H activation enables a concise total synthesis of quinine and analogues with enhanced antimalarial activity (Publications)
We report a novel approach to the classical natural product quinine that is based on two stereoselective key steps, namely a C-H activation and an aldol reaction, to unite the two heterocyclic moietie
Mathematical modelling of the impact of expanding levels of malaria control interventions on <em>Plasmodium vivax</em> (Publications)
Plasmodium vivax poses unique challenges for malaria control and elimination, notably the potential for relapses to maintain transmission in the face of drug-based treatment and vector control strateg
