Overview: mycolactone, the macrolide toxin of <em>Mycobacterium ulcerans</em> (Publications)
The acquisition by a Mycobacterium marinum-like progenitor of a plasmid encoding enzymes for the biosynthesis of the highly potent macrolide toxin mycolactone has set off the evolution of M. ulcerans
Overview: <em>Mycobacterium ulcerans </em>disease (Buruli ulcer) (Publications)
Enhanced international research efforts since the establishment of the Global BU Initiative in 1998 by the WHO have helped to advance our understanding of the epidemiology, and pathogenesis of Mycobac
Clinical diversity and treatment results in tegumentary leishmaniasis: a European clinical report in 459 patients (Publications)
BACKGROUND: Cutaneous leishmaniasis (CL) is frequent in travellers and can involve oro-nasal mucosae. Clinical presentation impacts therapeutic management. METHODOLOGY: Demographic and clinical data f
Chronic wounds in Sierra Leone: searching for Buruli ulcer, a NTD caused b<em>y Mycobacterium ulcerans</em>, at Masanga Hospital (Publications)
BACKGROUND: Chronic wounds pose a significant healthcare burden in low- and middle-income countries. Buruli ulcer (BU), caused by Mycobacterium ulcerans infection, causes wounds with high morbidity an
Leprosy in wild chimpanzees (Publications)
Humans are considered as the main host for Mycobacterium leprae(1), the aetiological agent of leprosy, but spillover has occurred to other mammals that are now maintenance hosts, such as nine-banded a
Challenges and experiences in linking community level reported out-of-pocket health expenditures to health provider recorded health expenditures:... (Publications)
Out of pocket health payment (OOPs) has been identified by the System of Health Accounts (SHA) as the largest source of health care financing in most low and middle-income countries. This means that m
Global estimates of the implications of COVID-19-related preprimary school closures for children's instructional access, development, learning, and... (Publications)
Observational data collected prior to the pandemic (between 2004 and 2019) were used to simulate the potential consequences of early childhood care and education (ECCE) service closures on the estimat
Discovery and structure-activity relationships of quinazolinone-2-carboxamide derivatives as novel orally efficacious antimalarials (Publications)
A phenotypic high-throughput screen allowed discovery of quinazolinone-2-carboxamide derivatives as a novel antimalarial scaffold. Structure-activity relationship studies led to identification of a po
The effect of exposure to radiofrequency fields on cancer risk in the general and working population: a protocol for a systematic review of human... (Publications)
BACKGROUND: The World Health Organization (WHO) has an ongoing project to assess potential health effects of exposure to radiofrequency electromagnetic fields (RF-EMF) in the general and working popul
