Tambjamines as fast-acting multistage antimalarials (Publications)
Well-tolerated and novel antimalarials that can combat multiple stages of the parasite life cycle are desirable but challenging to discover and develop. Herein, we report results for natural product-i
One-year impact of behavioural interventions on schistosomiasis-related knowledge, attitude and practices of primary schoolchildren in Pemba, Tanzania (Publications)
BACKGROUND: Elimination of schistosomiasis as a public health problem and interruption of transmission in selected areas are goals set by the World Health Organization for 2030. Behaviour change commu
Ambient air pollution exposure and incidence of cataract surgery: the prospective 3City-Alienor study (Publications)
PURPOSE: Cataract, the leading cause of blindness worldwide, is a multifactorial disease involving oxidative stress mechanisms. The aim of our study was to investigate the relationship between air pol
Meteorological factors, population immunity, and COVID-19 incidence: a global multi-city analysis (Publications)
OBJECTIVES: While COVID-19 continues to challenge the world, meteorological variables are thought to impact COVID-19 transmission. Previous studies showed evidence of negative associations between hig
Serum pentosidine in relation to obesity in patients with type 2 diabetes and healthy controls (Publications)
Pentosidine (PEN), a surrogate marker of advanced glycation end-product formation, reflects increased non-enzymatic cross-linking in bone collagen, which is thought to be an important determinant of b
Fecal carriage of ESBL-producing <em>E. coli </em>and genetic characterization in rural children and livestock in the Somali region, Ethiopia: a One... (Publications)
BACKGROUND: The emergence and spread of Extended-Spectrum Beta-Lactamase (ESBL)-producing Escherichia coli pose significant challenges for treatment of infections globally. This challenge is exacerbat
Insights into the biology and insecticide susceptibility of the secondary malaria vector <em>Anopheles parensis</em> in an area with long-term use of... (Publications)
BACKGROUND: The Anopheles funestus group includes at least 11 sibling species, with Anopheles funestus Giles being the most studied and significant malaria vector. Other species, like Anopheles parens
Representation of authors and editors from countries with different human development indexes in the leading literature on tropical medicine: survey... (Publications)
OBJECTIVE: To assess the current international representation of members of editorial and advisory boards and authors in the leading peer reviewed literature on tropical medicine. DESIGN: Systematic r
TKK130 is a 3-hydroxy-propanamidine (HPA) with potent antimalarial <em>in vivo</em> activity and a high barrier to resistance (Publications)
Malaria continues to pose a significant burden on populations in endemic areas and requires innovative treatment options. Here, we report the synthesis and preclinical evaluation of the novel 3-hydrox
Determinants of malaria infection among under five children in Gursum district of Somali region, eastern Ethiopia (Publications)
BACKGROUND: Despite significant efforts to control malaria infections in recent years, new infection rates continue to pose a major public health challenge in sub-Saharan Africa, including Ethiopia. T
