Methods for diagnosing proteinuria: when to use which test, and why (Publications)
Proteinuria plays a central role in the diagnosis of kidney disease and has a high prognostic value. The test methods used differ considerably regarding impact on test accuracy, sensitivity, and speci
The association of increased pre- and postnatal NO2 and PM2.5 exposure with the infant nasal microbiome composition and respiratory symptoms (Publications)
BACKGROUND: Little is known about the mediating role of nasal microbiome on the association between pre- and postnatal air pollution exposure and subsequent respiratory morbidity in infancy. We aimed
Trichuriasis in human patients from Côte d'Ivoire caused by novel <em>Trichuris incognita</em> species with low sensitivity to albendazole/ivermectin... (Publications)
Albendazole/ivermectin combination therapy is a promising alternative to benzimidazole monotherapy alone for Trichuris trichiura control. We used fecal DNA metabarcoding to genetically characterize Tr
Praziquantel and factor H recruitment differentially affect the susceptibility of <em>Schistosoma mansoni</em> to complement-mediated damage (Publications)
BACKGROUND: Schistosomes are highly efficient evaders of human immunity, as evident by their ability to survive in human blood for years. How they protect themselves against the constant attack by a k
Efficacy and safety of albendazole alone versus albendazole in combination with ivermectin for the treatment of <em>Trichuris trichiura</em>... (Publications)
Trichuris trichiura, a soil-transmitted helminth (STH), often persists after a single dose of anthelminthic treatment. To overcome limited efficacy against T. trichiura of benzimidazoles (albendazole
Air pollution mixture complexity and its effect on PM2.5-related mortality: a multicountry time-series study in 264 cities (Publications)
BACKGROUND: Fine particulate matter (PM(2.5)) occurs within a mixture of other pollutant gases that interact and impact its composition and toxicity. To characterize the local toxicity of PM(2.5), it
Whole genome sequencing of <em>M. tuberculosis</em> for disease control in high-burden settings: study protocol for a cluster randomized controlled... (Publications)
BACKGROUND: Retrospective and descriptive molecular epidemiology studies have shown that Mycobacterium tuberculosis whole genome sequencing can identify outbreaks and disease transmission events with
