Common SIRT1 variants modify the effect of abdominal adipose tissue on aging-related lung function decline (Publications)
Lung function is an independent predictor of mortality and serves as an aging marker in never smokers. The protein sirtuin-1 of gene SIRT1 has profound anti-inflammatory effects and regulates metaboli
A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order (Publications)
BACKGROUND: Hay fever or seasonal allergic rhinitis (AR) is a chronic disorder associated with IgE sensitization to grass. The underlying genetic variants have not been studied comprehensively. There
Differences in indoor versus outdoor concentrations of ultrafine particles, PM2.5, PMabsorbance and NO2 in Swiss homes (Publications)
Indoor air quality is a growing concern as we spend the majority of time indoors and as new buildings are increasingly airtight for energy saving purposes. For a better understanding of residential in
Genetic heterogeneity of asthma phenotypes identified by a clustering approach (Publications)
The aim was to identify genetic variants associated with refined asthma phenotypes enabling to take into account multiple features of the disease.Latent class analysis (LCA) was applied in 3001 adults
Socioeconomic status and childhood leukemia incidence in Switzerland (Publications)
Socioeconomic status (SES) discrepancies exist for child and adult cancer morbidity and are a major public health concern. In this Swiss population-based matched case-control study on the etiology of
Effects of passive smoking on heart rate variability, heart rate and blood pressure: an observational study (Publications)
Background Exposure to environmental tobacco smoke (ETS) has been shown to increase the risk for cardiovascular diseases and death, and autonomic dysfunction (specifically, reduced heart rate variabil
Effectiveness and equity of the Tanzania National Voucher Scheme for mosquito nets over 10 years of implementation (Publications)
BACKGROUND: The Tanzania National Voucher Scheme (TNVS) was a public private partnership managed by the Ministry of Health that provided pregnant women and infants with highly subsidized (long-lasting
Passive smoking exposure among adults and the dynamics of respiratory symptoms in a prospective multicenter cohort study (Publications)
OBJECTIVES: The aim of this study was to measure the effects of past exposure to environmental tobacco smoke on the day-to-day dynamics of four respiratory-symptom classes in a diary study including a
Does systemic lidocaine reduce ketamine requirements for endotracheal intubation in calves? (Publications)
OBJECTIVE: To investigate whether an intravenous (IV) lidocaine bolus in calves premedicated with xylazine-butorphanol reduces the amount of ketamine required to allow endotracheal intubation. STUDY D