Recherche de *.

1. A low-frequency inactivating akt2 variant enriched in the Finnish population is associated with fasting insulin levels and type 2 diabetes risk (Publications)

   A low-frequency inactivating akt2 variant enriched in the Finnish population is associated with fasting insulin levels and type 2 diabetes risk

   Pertinence:

   To identify novel coding association signals and facilitate characterization of mechanisms influencing glycemic traits and type 2 diabetes risk, we analyzed 109,215 variants derived from exome array g

2. Home- and community-based growth monitoring to reduce early life growth faltering: an open-label, cluster-randomized controlled trial (Publications)

   Home- and community-based growth monitoring to reduce early life growth faltering: an open-label, cluster-randomized controlled trial

   Pertinence:

   Background: Despite the continued high prevalence of faltering growth, height monitoring remains limited in many low- and middle-income countries.Objective: The objective of this study was to test whe

3. RTS,S/AS01E malaria vaccine induces memory and polyfunctional T cell responses in a pediatric African phase III trial (Publications)

   RTS,S/AS01E malaria vaccine induces memory and polyfunctional T cell responses in a pediatric African phase III trial

   Pertinence:

4. When patients fail UNAIDS' last 90-the "failure cascade" beyond 90-90-90 in rural Lesotho, Southern Africa: a prospective cohort study (Publications)

   When patients fail UNAIDS' last 90-the "failure cascade" beyond 90-90-90 in rural Lesotho, Southern Africa: a prospective cohort study

   Pertinence:

5. Cherchez l'electron (Publications)

   Cherchez l'electron

   Pertinence:

   Who wouldn't want to have a drug that is activated only in the target cell? Prodrugs that are metabolically triggered inside the pathogen but not in the host are an attractive concept in antimicrobial

6. Alkamides from <em>Anacyclus pyrethrum</em> L. and their <em>in vitro</em> antiprotozoal activity (Publications)

   Alkamides from <em>Anacyclus pyrethrum</em> L. and their <em>in vitro</em> antiprotozoal activity

   Pertinence:

   In our ongoing study to evaluate the antiprotozoal activity of alkamides from Asteraceae, a dichloromethane extract from the roots of Anacycluspyrethrum L. showed a moderate in vitro activity against

7. PCR-based verification of positive rapid diagnostic tests for intestinal protozoa infections with variable test band intensity (Publications)

   PCR-based verification of positive rapid diagnostic tests for intestinal protozoa infections with variable test band intensity

   Pertinence:

   Stool-based rapid diagnostic tests (RDTs) for pathogenic intestinal protozoa (e.g. Cryptosporidium spp. and Giardia intestinalis) allow for prompt diagnosis and treatment in resource-constrained setti

8. Cohort profile: the Kilombero and Ulanga Antiretroviral Cohort (KIULARCO): a prospective HIV cohort in rural Tanzania (Publications)

   Cohort profile: the Kilombero and Ulanga Antiretroviral Cohort (KIULARCO): a prospective HIV cohort in rural Tanzania

   Pertinence:

   BACKGROUND: The Kilombero and Ulanga Antiretroviral Cohort (KIULARCO) is a single-site, open and ongoing prospective cohort of people living with human immunodeficiency virus (PLWHIV) established in 2

9. Steroid alkaloids from <em>Holarrhena africana</em> with strong activity against <em>Trypanosoma brucei rhodesiense</em> (Publications)

   Steroid alkaloids from <em>Holarrhena africana</em> with strong activity against <em>Trypanosoma brucei rhodesiense</em>

   Pertinence:

   In our continued search for natural compounds with activity against Trypanosoma brucei, causative agent of human African trypanosomiasis (HAT, "sleeping sickness"), we have investigated extracts from

10. Mobile-phone and handheld microscopy for neglected tropical diseases (Publications)

    Mobile-phone and handheld microscopy for neglected tropical diseases

    Pertinence: