Group | Environmental Exposure Modelling

The physical and social environment in which we live - and how we move around our activity space - plays an important role in our health and well-being. We explore the integral connection between health and place with an emphasis on the built environment, including both areas with pollution (e.g. air pollution, noise, radon, pesticides) and those that can be health promoting (e.g. green spaces and natural environments). Our epidemiological analyses are underpinned state-of-the-art spatio-temporal environmental exposure modelling techniques, often within a Geographic Information System (GIS) environment, exploiting Earth Observation and ancillary data.

Big Data Challenges in Exposure Science

As health data are subject to data protection, innovation in exposure assignment and processing of big data are crucial. One of our key research aims is to solve issues related to these challenges, from the application of novel statistical techniques (e.g. machine learning) to the development of harmonized environmental exposure databases for large populations to support vital collaborative research on important environmental health issues faced by today’s society.

Key Projects

EXPANSE: EXposome Powered tools for healthy living in urbAN SEttings

The main aim of the EXPANSE project is to address one of the most pertinent questions for urban planners, policy makers, and inhabitants in Europe: “How to maximize one’s health in a modern urban environment?” EXPANSE will translate its insights and innovations into research and dissemination tools that will be openly accessible via the EXPANSE toolbox. By applying innovative ethics-by-design throughout the project, the social and ethical acceptability of these tools will be safeguarded. Tool discoverability and accessibility will be stimulated through the EXPANSE hub in which citizens, public sector policy makers, and private sector companies collectively participate. Further information

MOBI-AIR: Accounting for MOBility in AIR pollution exposure estimates in studies on long-term health effects

Large scale epidemiological studies investigating long-term health effects of air pollution can typically only consider the residential locations of the participants, thereby ignoring the space-time activity patterns that likely influence total exposure. People are mobile and can be exposed to considerably different levels of air pollution or air pollution mixtures when inside vs. outside, commuting, recreating, or working. Neglecting these mechanisms in exposure assessment may lead to incorrect distributions of exposure over the population which may lead to incorrect exposure health relations in epidemiological studies. The main aim of this study is to assess whether more sophisticated estimates of individual exposure, considering population mobility, decreases the bias in health studies. Further information

PaRTERRE - Prospective cohort study on skin cancer and residential radon exposure

This large study will substantially contribute to a better understanding of the risk factors for skin cancer. After Australia and New Zealand, Switzerland is ranking third worldwide for malignant melanoma incidence. In addition to UV radiation, recent studies found indications that radon may increase the risk for skin cancer. Radon levels in Switzerland are higher than in most other countries. To know if there is a link between household radon exposure and skin cancer is thus of high public health relevance.

Latest Publications

All Publications

Bouma F et al. Comparison of air pollution exposure assessment methods and the association with children's respiratory health. Environ Int. 2025;198(in press). DOI: 10.1016/j.envint.2025.109407

Gayraud L et al. Ambient air pollution exposure and incidence of cataract surgery: the prospective 3City-Alienor study. Acta Ophthalmol. 2025;103(3):e192-e199. DOI: 10.1111/aos.16790

Jeong A et al. Lung function-associated exposome profile in the era of climate change: pooled analysis of 8 population-based European cohorts within the EXPANSE project. Environ Int. 2025;196:109269. DOI: 10.1016/j.envint.2025.109269

Künstle N et al. The association of increased pre- and postnatal NO2 and PM2.5 exposure with the infant nasal microbiome composition and respiratory symptoms. Environ Res. 2025;267:120694. DOI: 10.1016/j.envres.2024.120694

Ndiaye A et al. Associations between long-term air pollution exposure and mortality and cardiovascular morbidity: a comparison of mobility-integrated and residential-only exposure assessment. Environ Int. 2025;198:109387. DOI: 10.1016/j.envint.2025.109387