Unit | Clinical Operations

Over 20 Years' Experience as Clinical Trials Service Provider

Swiss TPH has extensive expertise in clinical trial service provision, with a successful track record of operating and facilitating research in resource-constraint settings for over 20 years. We understand the barriers to conducting clinical trials in difficult settings and offer strategic, customised solutions with a high level of flexibility. We appreciate the intricacies of strategic planning in these settings and aim to deliver the highest quality data for clinical trials tailored to each unique project.

We do this through:

  1. Local “know-how” of regional context
  2. Understanding the “patient pathway” in various settings
  3. Academic and scientific innovation
  4. Clinical expertise and management

We propose study designs and monitoring solutions to promote evidence-based practices that lead to meaningful, sustainable and effective outputs. By working with healthcare providers in an open, transparent manner, we enrich our local understanding and thus enhance the quality to deliver customer-focused clinical trials.

Fexinidazole against African Human Trypanosomiasis

Human Africa Trypanosomiasis is a life-threatening neglected disease. To date nifurtimox-eflornithine combined therapy (NECT) is the Standard Treatment for late-stage HAT. Nevertheless, NECT is still far from ideal given the environment in which HAT patients live. There is an urgent need to develop less toxic and easier-to-use products. One promising agent is Fexinidazole.

Link to Project

Pediatric Praziquantel Formulation for Treating Schistosomiasis

Schistosomes, parasitic blood flukes, cause the chronic disaese schistosomiasis. Today, the gold standard of treatment is praziquantel which is only suitable for adults and school-aged children. Thus, a palliative, effective and safe praziquantel formulation to treat young children is absolutely required. To reach this aim, the Pediatric Praziquantel Consortium was founded in 2012.

Link to Project

Treatment of Multidrug-Resistant Tuberculosis

Tuberculosis is one of the most deadly infectious diseases in the world. Treatment is complex especially in case of multidrug-resistant tuberculosis. Particularly patients in low-resource countries often lack access or do not complete treatment regimen. TB PRACTECAL is a pioneering new clinical trial aiming to find a radically improved course of treatment for drug-resistant tuberculosis.

Link to Project

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Selected projects at this location: