Vaccines against malaria: perspectives from Papua New Guinea (Publications)
perspectives on malaria vaccines. Building on a long history of malaria research, in this article we review past achievements, highlight current research and outline future directions in malaria vaccine research [...] transmission of all four species of human malaria, a full range of malaria endemicities, well described epidemiology and a demonstrated capacity to evaluate a malaria vaccine, PNG currently has the only field [...] Despite its small population and isolated location Papua New Guinea...
The economic cost to households of childhood malaria in Papua New Guinea: a focus on intra-country variation (Publications)
BACKGROUND We compare direct and indirect household costs associated with malaria treatment for children
Effectiveness of artemether/lumefantrine for the treatment of uncomplicated <em>Plasmodium vivax</em> and <em>P. falciparum</em> malaria in young... (Publications)
uncomplicated Plasmodium falciparum (Pf) malaria, while chloroquine is still widely used for non-Pf infections. A common treatment for both vivax and falciparum malaria would be welcome.Methods. A longitudinal [...] had an infection confirmed by blood slide (BS) examination. Of these, 594 Pv and 332 Pf clinical malaria cases were included in the primary effectiveness analysis. Clinical treatment failure rates at 7 [...] 7, 28 and 42 days were 0.2%, 2.2% and 12.0% for Pv and 0.3%, 1.2% and 3.6%...
Reproduction numbers in malaria and their implications (Publications)
important for analyzing the effects of interventions against malaria. This has importance for both formal modeling of malaria and for planning malaria intervention strategies in the field [...] The malariologist Lewis Wendell Hackett famously observed that, "Like chess, (malaria) is played with a few pieces, but is capable of an infinite variety of situations". This paper discusses one such piece
Is fever a good sign for clinical malaria in surveys of endemic communities? (Publications)
ic sign of clinical malaria, many Plasmodium falciparum malaria cases in endemic areas do not present with measurable temperature elevations. In a field study in Tanzania, malaria morbidity was defined [...] reported illness associated with malaria parasite densities higher than those in healthy individuals. Without diagnosis of individual episodes, prevalences of malaria-attributable morbidity of 9.8% in [...] 5-9 years of age were estimated. No illness was considered to be due to malaria in...