Higher complexity of infection and genetic diversity of <em>Plasmodium vivax </em>than <em>Plasmodium falciparum</em> across all malaria transmission... (Publications)
New Guinea (PNG) to evaluate transmission dynamics across the country. In 2008-2009, a nationwide malaria indicator survey collected 8,936 samples from all 16 endemic provinces of PNG. Of these, 892 positive
An investment case to prevent the reintroduction of malaria in Sri Lanka (Publications)
in reducing the burden of malaria, recording no locally transmitted malaria cases since November 2012 and zero deaths since 2007. The country was recently certified as malaria free by World Health Organization [...] due to persistent receptivity and vulnerability to malaria transmission. Maintaining the gains will require continued sustainability to the malaria program to maintain the activities aimed at preventing [...] economic cost of the malaria program in 2014 was estimated at U.S. dollars...
Susceptibility of <em>Anopheles gambiae</em> to insecticides used for malaria vector control in Rwanda (Publications)
a major threat to the gains made in malaria control. To monitor the presence and possible emergence of resistance against a variety of insecticides used for malaria control in Rwanda, nationwide insecticide [...] using the synergist PBO. CONCLUSION: This is the first nationwide study of insecticide resistance in malaria vectors in Rwanda. It shows the gradual increase of insecticide resistance to pyrethroids (lambd [...] testing and implement an insecticide resistance management strategy to...
Nouvelles approches pour la prévention de la malaria chez le voyageur (Publications)
Malaria is declining in many tropical countries. This reduction challenges our usual preventive strategies. In moderate to low risk areas, the Swiss guidelines recommend a stand-by emergency treatment [...] making through three clinical studies. The first showed that travelers visiting moderate to low risk malaria areas prefer a standby emergency treatment rather than chemoprophylaxis. The second study investigates
Sensitive and accurate quantification of human malaria parasites using droplet digital PCR (ddPCR) (Publications)
of parasite density in the human host is essential for understanding the biology and pathology of malaria. Semi-quantitative molecular methods are widely applied, but the need for an external standard curve
Mefloquine at the crossroads? Implications for malaria chemoprophylaxis in Europa [Commentary] (Publications)
mefloquine. Some malaria prevention advisors question the scientific basis for the restrictions and suggest that this cost-effective, anti-malarial drug will be displaced as a first-line anti-malaria medication [...] the new recommendations for malaria prophylaxis that have been adapted by Switzerland, Germany, Austria and Italy where chemoprophylaxis use is restricted to high-risk malaria-endemic areas. [...] Since its introduction to the market in 1985, mefloquine has been used for malaria...
Gametocyte carriage in uncomplicated <em>Plasmodium falciparum</em> malaria following treatment with artemisinin combination therapy: a systematic... (Publications)
BACKGROUND: Gametocytes are responsible for transmission of malaria from human to mosquito. Artemisinin combination therapy (ACT) reduces post-treatment gametocyte carriage, dependent upon host, parasite [...] pharmacodynamic factors. The gametocytocidal properties of antimalarial drugs are important for malaria elimination efforts. An individual patient clinical data meta-analysis was undertaken to identify