Safety and immunogenicity of radiation-attenuated PfSPZ vaccine in equatoguinean infants, children, and adults (Publications)
age. Antibody responses in children were greater than in adults protected against controlled human malaria infection. Robust immunogenicity, combined with a benign AE profile, indicates children are an ideal
Time of exposure and assessment influence the mortality induced by insecticides against metabolic resistant mosquitoes (Publications)
BACKGROUND: Increasing metabolic resistance in malaria vector mosquitoes resulted in the development of insecticide-treated nets (ITNs) with active ingredients (AI) that target them. Bioassays that accurately
Microsatellite and mitochondrial genetic differentiation of <em>Anopheles arabiensis</em> (Diptera: Culicidae) from western Kenya, the Great Rift... (Publications)
The population genetic structure of the African malaria vector Anopheles arabiensis from western Kenya, the Great Rift Valley, and coastal Kenya was investigated using 12 microsatellite loci and a partial
Asymptomatic <em>Plasmodium falciparum</em> infections may not be shortened by acquired immunity (Publications)
naturally acquired immunity (NAI) can shorten infections, despite the potential implications for malaria control and elimination as well as for basic research. METHODS: Data on the presence of P. falciparum
Prevalence and factors associated with convulsive status epilepticus in Africans with epilepsy (Publications)
, acute encephalopathy, previous hospitalization, and presence of antibody titers to falciparum malaria and HIV; these differed across sites. Burns (15%), lack of education (49%), being single (77%), and
Metabolic, pharmacokinetic, and activity profile of the liver stage antimalarial (RC-12) (Publications)
identified Phase I metabolites had no in vitro activity against P. vivax or P. cynomolgi liver-stage malaria parasites, we suggest that there may be additional unidentified active metabolites of 1 or that the
The antiprotozoal activity of methylated flavonoids from <em>Ageratum conyzoides</em> L (Publications)
against Leishmania donovani (Kala-Azar, IC(50)=3.4 microg/mL) as well as Plasmodium falciparum (Malaria tropica, IC(50)=8.0 microg/mL). In the current study, we sought for potentially active constituents
The epidemiology of multiple <em>Plasmodium falciparum</em> infections. 10. Effect of insecticide-treated bed nets on the dynamics of multiple... (Publications)
areas of high P. falciparum endemicity, ITNs have little effect on the establishment of chronic malaria infection.
Recours aux soins et utilisation des services de santé à Nouakchott (Mauritanie): inégalités spatiales ou pesanteurs sociales? (Publications)
or weight loss) seen to suggest more serious diseases, such as tuberculosis, meningitis or severe malaria. Geographic accessibility of health services was relatively good (70 %). It was the economic, so
<em>In vitro</em> and<em> in vivo</em> activity of Solithromycin (CEM-101) against <em>Plasmodium</em> species (Publications)
the same dose required for artesunate or chloroquine to achieve 100% cure rates in this rodent malaria model. These promising in vitro and in vivo data support further investigations into the development