Sébastien Gagneux, Professor, PhD

Function(s)
Head of Department, Head of Unit

Organisational Entity

Sébastien Gagneux is Head of the Department of Medical Parasitology and Infection Biology at the Swiss Tropical and Public Health Institute (Swiss TPH) and Professor of Infection Biology at the University of Basel. After receiving his PhD from the University of Basel, he worked as a postdoctoral fellow at Stanford University and at the Institute for Systems Biology in Seattle, USA. He then started his own laboratory at the MRC National Institute for Medical Research in London, UK, before joining Swiss TPH. His research focuses on the ecology and evolution of Mycobacterium tuberculosis with a particular focus on antimicrobial resistance.

 

Latest Publications

All Publications

Arbués A, Schmidiger S, Reinhard M, Borrell S, Gagneux S, Portevin D. Soluble immune mediators orchestrate protective in vitro granulomatous responses across Mycobacterium tuberculosis complex lineages. Elife. 2025;13. DOI: 10.7554/eLife.99062

Goig G.A et al. Transmission as a key driver of resistance to the new tuberculosis drugs. N Engl J Med. 2025;392(1):97-99. DOI: 10.1056/NEJMc2404644

Goig G.A et al. Ecology, global diversity and evolutionary mechanisms in the Mycobacterium tuberculosis complex. Nat Rev Microbiol. 2025(in press). DOI: 10.1038/s41579-025-01159-w

March V.F.A et al. Drug-induced differential culturability in diverse strains of Mycobacterium tuberculosis. Sci Rep. 2025;15:3588. DOI: 10.1038/s41598-024-85092-7

Stritt C et al. Gene conversion and duplication contribute to genetic variation in an outbreak of Mycobacterium tuberculosis. Microb Genom. 2025;11(5):001396. DOI: 10.1099/mgen.0.001396

Tutumlu T.K et al. Mycobacteria beyond disease. Trends Microbiol. 2025(in press). DOI: 10.1016/j.tim.2025.04.008

Windels E.M et al. Onset of infectiousness explains differences in transmissibility across Mycobacterium tuberculosis lineages. Epidemics. 2025;51:100821. DOI: 10.1016/j.epidem.2025.100821

Xu Z.M et al. Genome-to-genome analysis reveals associations between human and mycobacterial genetic variation in tuberculosis patients from Tanzania. BMC Med Genomics. 2025;18:99. DOI: 10.1186/s12920-025-02164-x

Cirillo D et al. A successful UN High-Level Meeting on antimicrobial resistance must build on the 2023 UN High-Level Meeting on tuberculosis. Lancet Glob Health. 2024;12(8):e1225-e1226. DOI: 10.1016/s2214-109x(24)00229-8

Conceição E.C et al. A genome-focused investigation reveals the emergence of a Mycobacterium tuberculosis strain related to multidrug-resistant tuberculosis in the Amazon region of Brazil. Microorganisms. 2024;12(9):1817. DOI: 10.3390/microorganisms12091817