Publications

Loiseau C, Windels E.M, Gygli S.M, Jugheli L, Maghradze N, Brites D, Ross A, Goig G, Reinhard M, Borrell S, Trauner A, Dötsch A, Aspindzelashvili R, Denes R, Reither K, Beisel C, Tukvadze N, Avaliani Z, Stadler T, Gagneux S. The relative transmission fitness of multidrug-resistant Mycobacterium tuberculosis in a drug resistance hotspot. Nat Commun. 2023;14:1988. DOI: 10.1038/s41467-023-37719-y

Zwyer M, Rutaihwa L.K, Windels E, Hella J, Menardo F, Sasamalo M, Sommer G, Schmülling L, Borrell S, Reinhard M, Dötsch A, Hiza H, Stritt C, Sikalengo G, Fenner L, De Jong B.C, Kato-Maeda M, Jugheli L, Ernst J.D, Niemann S, Jeljeli L, Ballif M, Egger M, Rakotosamimanana N, Yeboah-Manu D, Asare P, Malla B, Dou H.Y, Zetola N, Wilkinson R.J, Cox H, Carter E.J, Gnokoro J, Yotebieng M, Gotuzzo E, Abimiku A, Avihingsanon A, Xu Z.M, Fellay J, Portevin D, Reither K, Stadler T, Gagneux S, Brites D. Back-to-Africa introductions of Mycobacterium tuberculosis as the main cause of tuberculosis in Dar es Salaam, Tanzania. PLoS Pathog. 2023;19(4):e1010893. DOI: 10.1371/journal.ppat.1010893

Maghradze N, Jugheli L, Borrell S, Tukvadze N, Kempker R.R, Blumberg H.M, Gagneux S. Developing customized stepwise MIRU-VNTR typing for tuberculosis surveillance in Georgia. PLoS One. 2022;17(3):e0264472. DOI: 10.1371/journal.pone.0264472

Gygli S.M, Loiseau C, Jugheli L, Adamia N, Trauner A, Reinhard M, Ross A, Borrell S, Aspindzelashvili R, Maghradze N, Reither K, Beisel C, Tukvadze N, Avaliani Z, Gagneux S. Prisons as ecological drivers of fitness-compensated multidrug-resistant Mycobacterium tuberculosis. Nat Med. 2021;27:1171–1177. DOI: 10.1038/s41591-021-01358-x

Gygli S.M, Loiseau C, Jugheli L, Adamia N, Trauner A, Reinhard M, Ross A, Borrell S, Aspindzelashvili R, Maghradze N, Reither K, Beisel C, Tukvadze N, Avaliani Z, Gagneux S. Publisher Correction: Prisons as ecological drivers of fitness-compensated multidrug-resistant Mycobacterium tuberculosis. Nat Med. 2021;27(7):1308. DOI: 10.1038/s41591-021-01417-3

Menardo F, Rutaihwa L.K, Zwyer M, Borrell S, Comas I, Conceicao E.C, Coscolla M, Cox H, Joloba M, Dou H.Y, Feldmann J, Fenner L, Fyfe J, Gao Q, Garcia de Viedma D, Garcia-Basteiro A.L, Gygli S.M, Hella J, Hiza H, Jugheli L, Kamwela L, Kato-Maeda M, Liu Q, Ley S.D, Loiseau C, Mahasirimongkol S, Malla B, Palittapongarnpim P, Rakotosamimanana N, Rasolofo V, Reinhard M, Reither K, Sasamalo M, Silva Duarte R, Sola C, Suffys P, Batista Lima K.V, Yeboah-Manu D, Beisel C, Brites D, Gagneux S. Local adaptation in populations of Mycobacterium tuberculosis endemic to the Indian Ocean Rim. F1000Res. 2021;10:60. DOI: 10.12688/f1000research.28318.1

Maghradze N, Jugheli L, Borrell S, Tukvadze N, Aspindzelashvili R, Avaliani Z, Reither K, Gagneux S. Classifying recurrent Mycobacterium tuberculosis cases in Georgia using MIRU-VNTR typing. PLoS One. 2019;14(10):e0223610. DOI: 10.1371/journal.pone.0223610

Rutaihwa L, Menardo F, Stucki D, Gygli S.M, Ley S.D, Malla B, Feldmann J, Borrell S, Beisel C, Middelkoop K, Carter J.E, Diero L, Ballif M, Jugheli L, Reither K, Fenner L, Brites D, Gagneux S. Multiple introductions of Mycobacterium tuberculosis lineage 2-Beijing into Africa over centuries. Front Ecol Evol. 2019;7:112. DOI: 10.3389/fevo.2019.00112

Hiza H, Doulla B, Sasamalo M, Hella J, Kamwela L, Mhimbira F, Reither K, Gagneux S, Jugheli L, Fenner L. Preservation of sputum samples with cetylpyridinium chloride (CPC) for tuberculosis cultures and Xpert MTB/RIF in a low-income country. BMC Infect Dis. 2017;17:542. DOI: 10.1186/s12879-017-2642-z

Demers A.M, Venter A, Friedrich S.O, Rojas-Ponce G, Mapamba D, Jugheli L, Sasamalo M, Almeida D, Dorasamy A, Jentsch U, Gibson M, Everitt D, Eisenach K.D, Diacon A.H. Direct susceptibility testing of Mycobacterium tuberculosis for pyrazinamide using the BACTEC MGIT 960 system. J Clin Microbiol. 2016;54(5):1276-1281. DOI: 10.1128/JCM.03162-15

Petrone L, Cannas A, Vanini V, Cuzzi G, Aloi F, Nsubuga M, Sserunkuma J, Nazziwa R.A, Jugheli L, Lukindo T, Girardi E, Antinori A, Pucci L, Reither K, Goletti D. Blood and urine inducible protein 10 as potential markers of disease activity. Int J Tuberc Lung Dis. 2016;20(11):1554-1561. DOI: 10.5588/ijtld.16.0342

Pohl C, Rutaihwa L.K, Haraka F, Nsubuga M, Aloi F, Ntinginya N.E, Mapamba D, Heinrich N, Hoelscher M, Marais B.J, Jugheli L, Reiter M. Limited value of whole blood Xpert® MTB/RIF for diagnosing tuberculosis in children. J Infect. 2016;73(4):326-335. DOI: 10.1016/j.jinf.2016.04.041

Sikalengo G, Ramirez A, Faini D, Mwamelo K, Battegay M, Jugheli L, Hatz C, Reither K, Letang E. Tuberculous spondylitis diagnosed through Xpert MTB/RIF assay in urine: a case report. BMC Infect Dis. 2016;16:514. DOI: 10.1186/s12879-016-1844-0

Heinrich N, Dawson R, du Bois J, Narunsky K, Horwith G, Phipps A.J, Nacy C.A, Aarnoutse R.E, Boeree M.J, Gillespie S.H, Venter A, Henne S, Rachow A, Phillips P.P, Hoelscher M, Diacon A.H, Pan African Consortium for the Evaluation of Antituberculosis Antibiotics (PanACEA). Early phase evaluation of SQ109 alone and in combination with rifampicin in pulmonary TB patients. J Antimicrob Chemother. 2015;70(5):1558-1566. DOI: 10.1093/jac/dku553

Mhimbira F.A, Bholla M, Sasamalo M, Mukurasi W, Hella J, Jugheli L, Reither K. Detection of Mycobacterium tuberculosis by EasyNAT (TM) diagnostic kit in sputum samples from Tanzania. Trop Med Int Health, 2015;20(Suppl. 1):190. Abstracts of the 9th European Congress on Tropical Medicine and International Health, 6-10 September 2015, Basel, Switzerland

Mhimbira F.A, Bholla M, Sasamalo M, Mukurasi W, Hella J.J, Jugheli L, Reither K. Detection of Mycobacterium tuberculosis by EasyNAT diagnostic kit in sputum samples from Tanzania. J Clin Microbiol. 2015;53(4):1342-1344. DOI: 10.1128/JCM.03037-14

Petrone L, Cannas A, Aloi F, Nsubuga M, Sserumkuma J, Nazziwa R.A, Jugheli L, Lukindo T, Girardi E, Reither K, Goletti D. Blood or urine IP-10 cannot discriminate between active tuberculosis and respiratory diseases different from tuberculosis in children. Biomed Res Int. 2015;2015:ID 589471. DOI: 10.1155/2015/589471

Reither K, Jugheli L, Glass T.R, Sasamalo M, Mhimbira F.A, Weetjens B.J, Cox C, Edwards T.L, Mulder C, Beyene N.W, Mahoney A. Evaluation of giant African pouched rats for detection of pulmonary tuberculosis in patients from a high-endemic setting. PLoS One. 2015;10(10):e0135877. DOI: 10.1371/journal.pone.0135877

Reither K, Manyama C, Clowes P, Rachow A, Mapamba D, Steiner A, Ross A, Mfinanga E, Sasamalo M, Nsubuga M, Aloi F, Cirillo D, Jugheli L, Lwilla F. Xpert MTB/RIF assay for diagnosis of pulmonary tuberculosis in children: a prospective, multi-centre evaluation. J Infect. 2015;70(4):392-399. DOI: 10.1016/j.jinf.2014.10.003

Breuninger M, van Ginneken B, Philipsen R.H, Mhimbira F, Hella J.J, Lwilla F, van den Hombergh J, Ross A, Jugheli L, Wagner D, Reither K. Diagnostic accuracy of computer-aided detection of pulmonary tuberculosis in chest radiographs: a validation study from sub-Saharan Africa. PLoS One. 2014;9(9):e106381. DOI: 10.1371/journal.pone.0106381

Portevin D, Moukambi F, Clowes P, Bauer A, Chachage M, Ntinginya E.N, Mfinanga E, Said K, Haraka F, Rachow A, Saathoff E, Mpina M, Jugheli L, Lwilla F, Marais B.J, Hoelscher M, Daubenberger C, Reither K, Geldmacher C. Assessment of the novel T-cell activation marker-tuberculosis assay for diagnosis of active tuberculosis in children: a prospective proof-of-concept study. Lancet Infect Dis. 2014;14(10):931-938. DOI: 10.1016/S1473-3099(14)70884-9

Pohl C, Jugheli L, Haraka F, Mfinanga E, Said K, Reither K. Pulmonary aspergilloma: a treatment challenge in sub-Saharan Africa. PLoS Negl Trop Dis. 2013;7(10):e2352. DOI: 10.1371/journal.pntd.0002352