Publications

Schmidiger S, McCaffrey E.F, Schmidt J.M, Hameed O.A, Mpina M, Tumbo A, Mfinanga E, Haraka F, Hiza H, Sasamalo M, Hella J, Walch M, Fellay J, Gagneux S, Reither K, Carballido J.M, Arbués A, Portevin D. Granulysin antimicrobial activity promotes dormancy in Mycobacterium tuberculosis. Eur J Immunol. 2025;55(8):e70004. DOI: 10.1002/eji.70004

Hiza H, Zwyer M, Hella J, Arbués A, Sasamalo M, Borrell S, Xu Z.M, Ross A, Brites D, Fellay J, Reither K, Gagneux S, Portevin D. Bacterial diversity dominates variable macrophage responses of tuberculosis patients in Tanzania. Sci Rep. 2024;14:9287. DOI: 10.1038/s41598-024-60001-0

Hiza H, Hella J, Arbués A, Sasamalo M, Misana V, Fellay J, Gagneux S, Reither K, Portevin D. CD38 expression by antigen-specific CD4 t cells is significantly restored 5 months after treatment initiation independently of sputum bacterial load at the time of tuberculosis diagnosis. Front Med. 2022;9:821776. DOI: 10.3389/fmed.2022.821776

Hiza H, Hella J, Arbués A, Magani B, Sasamalo M, Gagneux S, Reither K, Portevin D. Case-control diagnostic accuracy study of a non-sputum CD38-based TAM-TB test from a single milliliter of blood. Sci Rep. 2021;11(1):13190. DOI: 10.1101/2021.03.10.21253246

Menardo F, Rutaihwa L.K, Zwyer M, Borrell S, Comas I, Conceicao E.C, Coscolla M, Cox H, Joloba M, Dou H.Y, Feldmann J, Fenner L, Fyfe J, Gao Q, Garcia de Viedma D, Garcia-Basteiro A.L, Gygli S.M, Hella J, Hiza H, Jugheli L, Kamwela L, Kato-Maeda M, Liu Q, Ley S.D, Loiseau C, Mahasirimongkol S, Malla B, Palittapongarnpim P, Rakotosamimanana N, Rasolofo V, Reinhard M, Reither K, Sasamalo M, Silva Duarte R, Sola C, Suffys P, Batista Lima K.V, Yeboah-Manu D, Beisel C, Brites D, Gagneux S. Local adaptation in populations of Mycobacterium tuberculosis endemic to the Indian Ocean Rim. F1000Res. 2021;10:60. DOI: 10.12688/f1000research.28318.1

Rutaihwa L.K, Sasamalo M, Jaleco A, Hella J, Kingazi A, Kamwela L, Kingalu A, Malewo B, Shirima R, Dötsch A, Feldmann J, Reinhard M, Borrell S, Brites D, Reither K, Doulla B, Fenner L, Gagneux S. Insights into the genetic diversity of Mycobacterium tuberculosis in Tanzania. PLoS One. 2019;14(4):e0206334. DOI: 10.1371/journal.pone.0206334

Hella J, Cercamondi C.I, Mhimbira F, Sasamalo M, Stoffel N, Zwahlen M, Bodmer T, Gagneux S, Reither K, Zimmermann M.B, Risch L, Fenner L. Anemia in tuberculosis cases and household controls from Tanzania: contribution of disease, coinfections, and the role of hepcidin. PLoS One. 2018;13(4):e0195985. DOI: 10.1371/journal.pone.0195985

Hiza H, Doulla B, Sasamalo M, Hella J, Kamwela L, Mhimbira F, Reither K, Gagneux S, Jugheli L, Fenner L. Preservation of sputum samples with cetylpyridinium chloride (CPC) for tuberculosis cultures and Xpert MTB/RIF in a low-income country. BMC Infect Dis. 2017;17:542. DOI: 10.1186/s12879-017-2642-z

Mhimbira F, Hella J, Said K, Kamwela L, Sasamalo M, Maroa T, Chiryamkubi M, Mhalu G, Schindler C, Reither K, Knopp S, Utzinger J, Gagneux S, Fenner L. Prevalence and clinical relevance of helminth co-infections among tuberculosis patients in urban Tanzania. PLoS Negl Trop Dis. 2017;11(2):e0005342. DOI: 10.1371/journal.pntd.0005342

Demers A.M, Venter A, Friedrich S.O, Rojas-Ponce G, Mapamba D, Jugheli L, Sasamalo M, Almeida D, Dorasamy A, Jentsch U, Gibson M, Everitt D, Eisenach K.D, Diacon A.H. Direct susceptibility testing of Mycobacterium tuberculosis for pyrazinamide using the BACTEC MGIT 960 system. J Clin Microbiol. 2016;54(5):1276-1281. DOI: 10.1128/JCM.03162-15

Hella J.J, Mhimbira F.A, Abdallah S, Maroa T.M, Sasamalo M, Kamwela L, Hiza H, Said K.I, Fenner L. When malnutrition meets TB and HIV: prevalence of microcytic hypochromic anaemia and associated risk factors among adult TB cases and household contacts in urban Dar es Salaam, Tanzania. Trop Med Int Health, 2015;20(Suppl. 1):79-80

Mbuba E, Makene V, Masanja H, Sasamalo M, Mwangoka G, Munuo L, Mhimbira F.A, Reither K, Dartois V, Mugittu K. Genetic diversity of Mycobacterium tuberculosis and mutation profiles in drug resistance associated genes in Bagamoyo District, Tanzania. Trop Med Int Health, 2015;20(Suppl. 1):198. Abstracts of the 9th European Congress on Tropical Medicine and International Health, 6-10 September 2015, Basel, Switzerland

Mhalu G, Hella J, Doulla B, Mhimbira F, Mtutu H, Hiza H, Sasamalo M, Rutaihwa L, Rieder H.L, Seimon T, Mutayoba B, Weiss M.G, Fenner L. Do instructional videos on sputum submission result in increased tuberculosis case detection? A randomized controlled trial. PLoS One. 2015;10(9):e0138413. DOI: 10.1371/journal.pone.0138413

Mhimbira F.A, Bholla M, Sasamalo M, Mukurasi W, Hella J, Jugheli L, Reither K. Detection of Mycobacterium tuberculosis by EasyNAT (TM) diagnostic kit in sputum samples from Tanzania. Trop Med Int Health, 2015;20(Suppl. 1):190. Abstracts of the 9th European Congress on Tropical Medicine and International Health, 6-10 September 2015, Basel, Switzerland

Mhimbira F.A, Bholla M, Sasamalo M, Mukurasi W, Hella J.J, Jugheli L, Reither K. Detection of Mycobacterium tuberculosis by EasyNAT diagnostic kit in sputum samples from Tanzania. J Clin Microbiol. 2015;53(4):1342-1344. DOI: 10.1128/JCM.03037-14

Reither K, Jugheli L, Glass T.R, Sasamalo M, Mhimbira F.A, Weetjens B.J, Cox C, Edwards T.L, Mulder C, Beyene N.W, Mahoney A. Evaluation of giant African pouched rats for detection of pulmonary tuberculosis in patients from a high-endemic setting. PLoS One. 2015;10(10):e0135877. DOI: 10.1371/journal.pone.0135877

Reither K, Manyama C, Clowes P, Rachow A, Mapamba D, Steiner A, Ross A, Mfinanga E, Sasamalo M, Nsubuga M, Aloi F, Cirillo D, Jugheli L, Lwilla F. Xpert MTB/RIF assay for diagnosis of pulmonary tuberculosis in children: a prospective, multi-centre evaluation. J Infect. 2015;70(4):392-399. DOI: 10.1016/j.jinf.2014.10.003

Rutaihwa L, Sasamalo M, Hella J, Borrell S, Feldmann J, Coscolla M, Fenner L, Gagneux S. Global genomic diversity and clinical consequences of Mycobacterium tuberculosis in a high-burden setting. Trop Med Int Health, 2015;20(Suppl. 1):190. Abstracts of the 9th European Congress on Tropical Medicine and International Health, 6-10 September 2015, Basel, Switzerland