Surveillance of molecular markers of <em>Plasmodium falciparum</em> artemisinin resistance (<em>kelch</em>13 mutations) in Papua New Guinea between... (Publications)
Plasmodium falciparum resistance to artemisinin-based combination therapy (ACT) is a global threat to malaria control and elimination efforts. Mutations in the P. falciparum kelch13 gene (Pfk13) that
A high-throughput cell- and virus-free assay shows reduced neutralization of SARS-CoV-2 variants by COVID-19 convalescent plasma (Publications)
The detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific antibodies in the serum of an individual indicates prior infection or vaccination. However, it provides limited i
Common haplotypes at the <em>CFH </em>locus and low-frequency variants in <em>CFHR2 </em>and <em>CFHR5 </em>associate with systemic FHR concentrations... (Publications)
Age-related macular degeneration (AMD) is the principal cause of blindness in the elderly population. A strong effect on AMD risk has been reported for genetic variants at the CFH locus, encompassing
Two-target quantitative PCR to predict library composition for shallow shotgun sequencing (Publications)
When determining human microbiota composition, shotgun sequencing is a powerful tool that can generate high-resolution taxonomic and functional information at once. However, the technique is limited b
Quantifying transmission fitness costs of multi-drug resistant tuberculosis (Publications)
As multi-drug resistant tuberculosis (MDR-TB) continues to spread, investigating the transmission potential of different drug-resistant strains becomes an ever more pressing topic in public health. Wh
Associations of air pollution and greenness with the nasal microbiota of healthy infants: a longitudinal study (Publications)
BACKGROUND: Air pollution and greenness are associated with short- and long-term respiratory health in children but the underlying mechanisms are only scarcely investigated. The nasal microbiota durin
The multidimensional comprehension of Chagas disease: contributions, approaches, challenges and opportunities from and beyond the information,... (Publications)
Chagas is a complex, multidimensional phenomenon in which political, economic, environmental, biomedical, epidemiological, psychological, and sociocultural factors intersect. Nonetheless, the hegemoni
Epidemiology of <em>Mycobacterium tuberculosis</em> lineages and strain clustering within urban and peri-urban settings in Ethiopia (Publications)
BACKGROUND: Previous work has shown differential predominance of certain Mycobacterium tuberculosis (M. tb) lineages and sub-lineages among different human populations in diverse geographic regions of
The double burden of malnutrition and dietary patterns in rural Central Java, Indonesia (Publications)
Background: Indonesia is undergoing a nutrition transition (NT) comprised of rising rates of over- weight/obesity and consumption of high fat food/snacks but is still struck by undernutrition, causing