Food-borne trematodiasis: current chemotherapy and advances with artemisinins and synthetic trioxolanes (Publications)
Over 40 million people are infected with food-borne trematodes and 750 million are at risk of food-borne trematodiasis, and yet this tropical disease is neglected. The current arsenal for the treatmen
Heteronuclear 19F-1H statistical total correlation spectroscopy as a tool in drug metabolism: study of flucloxacillin biotransformation (Publications)
We present a novel application of the heteronuclear statistical total correlation spectroscopy (HET-STOCSY) approach utilizing statistical correlation between one-dimensional 19F/1H NMR spectroscopic
Interactions of mefloquine with praziquantel in the <em>Schistosoma mansoni</em> mouse model and <em>in vitro</em> (Publications)
Objectives Mefloquine has interesting antischistosomal properties, hence it might be an attractive partner drug for combination treatment with praziquantel. The aim of this study was to evaluate activ
Trematocidal activity of praziquantel and artemisinin derivatives:<em> in vitro</em> and <em>in vivo</em> investigations with adult <em>Echinostoma... (Publications)
We examined the effects of praziquantel and the artemisinins on adult Echinostoma caproni. In vitro, both praziquantel and the artemisinins exhibited exposure-response relationships. In vivo, worm bur
Impact of a single exercise bout on energy expenditure and spontaneous physical activity of obese boys (Publications)
The main objective of the present study was to determine whether a structured, laboratory-based exercise task would modify the energy expenditure (EE) and the pattern of spontaneous physical activity
FLOTAC: a promising technique for detecting helminth eggs in human faeces (Publications)
There is a tendency to neglect diagnostic issues in the era of 'preventive chemotherapy' in human helminthiases. However, accurate diagnosis cannot be overemphasized for adequate patient management an