Identification and qualification of a new family of peptide endocannabinoids (Pepcans) showing negative allosteric modulation at CB1 receptors (Publications)
The alpha-hemoglobin-derived dodecapeptide RVD-hemopressin (RVDPVNFKLLSH) has been proposed to be an endogenous agonist for the cannabinoid receptor type-1 (CB1). To study this peptide we have raised
beta-Branched acyclic nucleoside analogues as inhibitors of <em>Plasmodium falciparum</em> dUTPase (Publications)
We report a series of beta-branched acyclic tritylated deoxyuridine analogues as inhibitors of Plasmodium falciparum deoxyuridine-5'-triphosphate nucleotidohydrolase (PfdUTPase), an enzyme involved in
Molecular approaches to field studies of malaria (Publications)
The third 'Molecular Approaches to Malaria' conference was held in Lorne, Australia, in February 2008 and provided extensive information on the application of molecular tools in field studies on malar
Factors determining household expenditure for tuberculosis and coping strategies in Tajikistan (Publications)
Objective: To investigate factors influencing expenditure levels and the use of potentially detrimental coping strategies among tuberculosis (TB) patients. For the purpose of the present study, potent
Synthesis, DNA binding and antileishmanial activity of low molecular weight bis-arylimidamides (Publications)
The effects of reducing the molecular weight of the antileishmanial compound DB766 on DNA binding affinity, antileishmanial activity and cytotoxicity are reported. The bis-arylimidamides were prepared