Potent inhibitors of malarial aspartic proteases, the plasmepsins, by hydroformylation of substituted 7-azanorbornenes (Publications)
The increasing prevalence of multidrug-resistant strains of the malarial parasite Plasmodium falciparum requires the urgent development of new therapeutic agents with novel modes of action. The vacuol
Synthesis and antiprotozoal activity of pyridyl analogues of pentamidine (Publications)
A series of novel pyridyl analogues 1-18 of antiprotozoal drug 1,5-bis(4-amidinophenoxy)pentane (pentamidine) has been synthesized and tested for in vitro activities against Trypanosoma brucei rhodesi
Synthesis and antiprotozoal activity of cationic 2-phenylbenzofurans (Publications)
A series of cationically substituted 2-phenylbenzofurans 1- 49 have been synthesized, and their in vitro antiprotozoal properties against Trypanosoma brucei rhodesiense, Plasmodium falciparum, and Lei
Comparison of two approaches for measuring household wealth <em>via</em> an asset-based index in rural and peri-urban settings of Hunan province,... (Publications)
ABSTRACT: BACKGROUND: There are growing concerns regarding inequities in health, with poverty being an important determinant of health, as well as a product of health status. Within the People's Repub
Risk factors for helminth infections in a rural and a peri-urban setting of the Dongting Lake area, People's Republic of China (Publications)
Schistosomiasis japonica and soil-transmitted helminthiasis are endemic parasitic diseases in the People's Republic of China (PR China). As very few studies have reported on the distribution and inter
Molecular modeling study and synthesis of novel dicationic flexible triaryl guanidines and imidamides as antiprotozoal agents (Publications)
A new series of fourteen dicationic flexible triaryl bis-guanidines 3a,b, bis-N-substituted guanidines 7a,b and 8a,b as well as bis-imidamides 9-12a,b having a 1,3- or 1,4-diphenoxybenzene scaffold ba
