Antiprotozoal activity profiling of approved drugs: a starting point toward drug repositioning (Publications)
Neglected tropical diseases cause significant morbidity and mortality and are a source of poverty in endemic countries. Only a few drugs are available to treat diseases such as leishmaniasis, Chagas'
Bacteria-induced egg hatching differs for <em>Trichuris muris</em> and <em>Trichuris suis</em> (Publications)
BACKGROUND: Eggs of the porcine whipworm Trichuris suis are currently explored in human clinical trials as a treatment of immune-mediated diseases. In this context, only the infective, embryonated egg
Pyrimidine salvage in <em>Trypanosoma brucei</em> bloodstream forms and the trypanocidal action of halogenated pyrimidines (Publications)
African trypanosomes are capable of both pyrimidine biosynthesis and salvage of pre-formed pyrimidines from the host. However, uptake of pyrimidines in bloodstream form trypanosomes has not been inves
