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1. Long-term exposure to transportation noise and air pollution in relation to incident diabetes in the SAPALDIA study (Publications)

   Long-term exposure to transportation noise and air pollution in relation to incident diabetes in the SAPALDIA study

   Relevanz:

   Background: Epidemiological studies have inconsistently linked transportation noise and air pollution (AP) with diabetes risk. Most studies have considered single noise sources and/or AP, but none has

2. Adult lung function and long-term air pollution exposure. ESCAPE: a multicentre cohort study and meta-analysis (Publications)

   Adult lung function and long-term air pollution exposure. ESCAPE: a multicentre cohort study and meta-analysis

   Relevanz:

   The chronic impact of ambient air pollutants on lung function in adults is not fully understood. The objective of this study was to investigate the association of long-term exposure to ambient air pol

3. Causal and synthetic associations of variants in the SERPINA gene cluster with alpha1-antitrypsin serum levels (Publications)

   Causal and synthetic associations of variants in the SERPINA gene cluster with alpha1-antitrypsin serum levels

   Relevanz:

   Several infrequent genetic polymorphisms in the SERPINA1 gene are known to substantially reduce concentration of alpha1-antitrypsin (AAT) in the blood. Since low AAT serum levels fail to protect pulmo

4. Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function (Publications)

   Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function

   Relevanz:

   BACKGROUND: Genome-wide association studies (GWAS) have identified numerous loci influencing cross-sectional lung function, but less is known about genes influencing longitudinal change in lung functi

5. The exposome in practice: design of the EXPOsOMICS project (Publications)

   The exposome in practice: design of the EXPOsOMICS project

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6. Long-term transportation noise annoyance is associated with subsequent lower levels of physical activity (Publications)

   Long-term transportation noise annoyance is associated with subsequent lower levels of physical activity

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7. Variability of reproductive history across the Swiss SAPALDIA cohort - Pattern and main determinants (Publications)

   Variability of reproductive history across the Swiss SAPALDIA cohort - Pattern and main determinants

   Relevanz:

   Background: Reproductive characteristics play an aetiological role for many diseases, including reproductive cancers. They have been shown to vary internationally and nationally, but have not yet been

8. Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis (Publications)

   Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

   Relevanz:

   Genetic association studies have identified 21 loci associated with atopic dermatitis risk predominantly in populations of European ancestry. To identify further susceptibility loci for this common, c

9. Kleinräumige Verteilung von Stickstoffdioxid (Publications)

   Kleinräumige Verteilung von Stickstoffdioxid

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10. Improved air quality and attenuated lung function decline: modification by obesity in the SAPALDIA cohort (Publications)

    Improved air quality and attenuated lung function decline: modification by obesity in the SAPALDIA cohort

    Relevanz:

    OBJECTIVE: Air pollution and obesity are hypothesized to contribute to accelerated lung function decline with age through their inflammatory properties. We investigated whether the previously reported