Efficacy and pharmacokinetics of OZ78 and MT04 against a natural infection with <em>Fasciola hepatica</em> in sheep (Publications)
Fasciolosis is a parasitosis caused by the food-borne trematode Fasciola spp. of major veterinary significance. Triclabendazole is the first line treatment in humans and animals but cases of resistanc
Missed opportunities among HIV-positive women to control viral replication during pregnancy and to have a vaginal delivery (Publications)
INTRODUCTION:: Most national guidelines for the prevention of mother-to-child transmission of HIV in Europe updated between 2001 and 2010 recommend vaginal deliveries for women with undetectable or ve
Patients routinely report more symptoms to experienced field enumerators than physicians in rural Côte d'Ivoire (Publications)
Medical history-taking is among the most powerful diagnostic tools for healthcare professionals. However, its accuracy and reliability are underexplored areas. The present post-hoc study compares medi
Prevalence of drug-resistance mutations and HIV-1 subtypes in a HIV-1 infected COHORT in rural Tanzania (Publications)
ABSTRACT The development of resistance mutations in drug-targeted HIV-1 genes compromises the success of antiretroviral therapy (ART) programmes. Genotyping of these mutations enables adjusted therape
Cotton dust, endotoxin and cancer mortality among the Shanghai textile workers cohort: a 30-year analysis (Publications)
BACKGROUND: Although occupational exposure to cotton dust and endotoxin is associated with adverse respiratory health, associations with cancer are unclear. We investigated cancer mortality in relatio
Air pollution and lung cancer incidence in 17 European cohorts: prospective analyses from the European Study of Cohorts for Air Pollution Effects... (Publications)
BACKGROUND: Ambient air pollution is suspected to cause lung cancer. We aimed to assess the association between long-term exposure to ambient air pollution and lung cancer incidence in European popula
Investigation of acyclic uridine amide and 5'-amido nucleoside analogues as potential inhibitors of the <em>Plasmodium falciparum</em> dUTPase (Publications)
Previously we have shown that trityl and diphenyl deoxyuridine derivatives and their acyclic analogues can inhibit Plasmodium falciparum dUTPase (PfdUTPase). We report the synthesis of conformationall
