Synthesis, stereoelectronic characterization and antiparasitic activity of new 1-benzenesulfonyl-2-methyl-1,2,3,4-tetrahydroquinolines (Publications)
The synthesis and full 3D structural characterization of nine new 1-benzenesulfonyl-2-methyl-1,2,3,4-tetrahydroquinoline derivatives are reported. These belong to a library whose rationale for the des
Parental smoking and children's respiratory health: independent effects of prenatal and postnatal exposure (Publications)
OBJECTIVES: Adverse effects have been reported of prenatal and/or postnatal passive exposure to smoking on children's health. Uncertainties remain about the relative importance of smoking at different
Diagnostic concordance of neurasthenia spectrum disorders in Pune, India (Publications)
BACKGROUND: Clinically significant fatigue or weakness is a common but understudied clinical problem in India. The applicability and relevance of Western clinical criteria in this setting are not stud
Nifurtimox-eflornithine combination therapy for second-stage African <em>Trypanosoma brucei gambiense</em> trypanosomiasis: a multicentre, randomised,... (Publications)
BACKGROUND: Human African trypanosomiasis (HAT; sleeping sickness) caused by Trypanosoma brucei gambiense is a fatal disease. Current treatment options for patients with second-stage disease are toxic
Imidazolopiperazines: lead optimization of the second-generation antimalarial agents (Publications)
On the basis of the initial success of optimization of a novel series of imidazolopiperazines, a second generation of compounds involving changes in the core piperazine ring was synthesized to improve
Vaccines against malaria: perspectives from Papua New Guinea (Publications)
Despite its small population and isolated location Papua New Guinea (PNG) with a malaria burden comparable to sub-Saharan Africa, its intense transmission of all four human Plasmodium species and an u
Cholesterol screening in childhood: results of a 9-year follow-up study in Swiss and Italian children in Switzerland (Publications)
Mass screening for blood cholesterol as part of routine preventive health care of children continues to be discussed in several countries. Results of longitudinal studies underline the importance of t