Immunosuppression and treatment-associated inflammatory response in patients with <em>Mycobacterium ulcerans</em> infection (Buruli ulcer) (Publications)
Buruli ulcer is a necrotizing skin disease caused by Mycobacterium ulcerans. Major necrosis with abundant clusters of extracellularly replicating mycobacteria and only minor leukocyte infiltration are
Diversity of human intestinal helminthiasis in Lao PDR (Publications)
Food-borne trematodiasis is an emerging public health problem, including in Lao PDR. We investigated the diversity of intestinal helminthes and polyparasitism in patients with hepatobiliary or intesti
Panorganismal metabolic response modelling of an experimental <em>Echinostoma caproni </em>infection in the mouse (Publications)
Metabolic profiling of host tissues and biofluids during parasitic infections can reveal new biomarker information and aid the elucidation of mechanisms of disease. The multicompartmental metabolic ef
The changing epidemiology of malaria in Ifakara Town, southern Tanzania (Publications)
Between 1995 and 2000 there were marked changes in the epidemiology of malaria in Ifakara, southern Tanzania. We documented these changes using parasitological and clinical data from a series of commu
Decline in air pollution and change in prevalence in respiratory symptoms and chronic obstructive pulmonary disease in elderly women (Publications)
BACKGROUND: While adverse effects of exposure to air pollutants on respiratory health are well studied, little is known about the effect of a reduction in air pollutants on chronic respiratory symptom
Benefit of a single preoperative dose of antibiotics in a sub-Saharan district hospital: minimal input, massive impact (Publications)
OBJECTIVE: To evaluate the impact of a single-shot preoperative antimicrobial prophylaxis (AMP) to reduce the rate of Surgical Site Infections (SSIs) in a rural sub-Saharan hospital. SUMMARY BACKGROUN
Systematic evaluation of extraction methods for multi-platform based metabotyping: application to the <em>Fasciola hepatica</em> metabolome (Publications)
Combining data from multiple analytical platforms is essential for comprehensive study of the molecular phenotype (metabotype) of a given biological sample. The metabolite profiles generated are intri
MADAP, a flexible clustering tool for the interpretation of one-dimensional genome annotation data (Publications)
A recurring task in the analysis of mass genome annotation data from high-throughput technologies is the identification of peaks or clusters in a noisy signal profile. Examples of such applications ar
