Clinical and epidemiologic phenotypes of childhood asthma (Publications)
Rationale: Clinical and epidemiologic approaches have identified two distinct sets of classifications for asthma and wheeze phenotypes. Objective: To compare epidemiologic phenotype definitions identi
A novel multiple-instance learning-based approach to computer-aided detection of tuberculosis on chest x-rays (Publications)
In order to reach performance levels comparable to those of human experts, computer-aided detection (CAD) systems are typically optimized by means of a supervised learning approach that relies on larg
Protection from childhood asthma and allergy in Alpine farm environments - the GABRIEL Advanced Studies (Publications)
BACKGROUND: Studies on the association of farm environments with asthma and atopy have repeatedly observed a protective effect of farming. However, no single specific farm-related exposure explaining
First results of phase 3 trial of RTS,S/AS01 malaria vaccine in African children (Publications)
Background An ongoing phase 3 study of the efficacy, safety, and immunogenicity of candidate malaria vaccine RTS,S/AS01 is being conducted in seven African countries. Methods From March 2009 through J
Evaluation of implementation, compliance and acceptance of partial smoking bans among hospitality workers before and after the Swiss Tobacco Control... (Publications)
BACKGROUND: The World Health Organization recommends uniform comprehensive smoking bans in public places. In Switzerland, regulations differ between various areas and are mostly incomplete for hospita
Tracking a tuberculosis outbreak over 21 years: strain-specific single nucleotide polymorphism-typing combined with targeted whole genome sequencing (Publications)
BACKGROUND: Whole genome sequencing (WGS) is increasingly used in molecular-epidemiological investigations of bacterial pathogens, despite cost- and time-intensive analyses. We combined strain-specifi
Meningococcal carriage in the African meningitis belt (Publications)
A meningococcal serogroup A polysaccharide/tetanus toxoid conjugate vaccine (PsA-TT) (MenAfriVac) is being deployed in countries of the African meningitis belt. Experience with other polysaccharide/pr