Dioncophylline E from Dioncophyllum thollonii, the first 7,3'-coupled dioncophyllaceous naphthylisoquinoline alkaloid (Publications)
The isolation and structural elucidation of dioncophylline E, a novel naphthylisoquinoline alkaloid from the rare West African liana Dioncophyllum thollonii, is described. The alkaloid displays an unu
Atropo-enantioselective total synthesis of knipholone and related antiplasmodial phenylanthraquinones (Publications)
The "lactone concept" has been efficiently employed for the first atropo-enantioselective synthesis of knipholone and related natural phenylanthraquinones. Besides the regio- and stereoselective const
The National Schistosomiasis Control Programme in Mali: objectives, organization, results (Publications)
Schistosomiasis control started regionally, in the Bandiagara district, and as a component of a dam-building project in 1978. In 1982 a national programme was created. Control was divided into three p
Acceptability of a prime vendor system in public healthcare facilities in Tanzania (Publications)
BACKGROUND: Pharmaceutical supply chain management in low- and middle-income countries has received substantial attention to address the shortage of medicines at peripheral facilities. The focus has b
The impact of maternal RSV vaccine to protect infants in Gavi-supported countries: estimates from two models (Publications)
BACKGROUND: Interventions to protect young infants against respiratory syncytial virus (RSV) are in advanced phases of development and are expected to be available in the foreseeable future. Gavi, the
Vaccine implementation factors affecting maternal tetanus immunization in low- and middle-income countries: results of the Maternal Immunization and... (Publications)
OBJECTIVES: To examine the characteristics of existing maternal tetanus immunization programmes for pregnant women in low- and middle-income countries (LMICs) and to identify and understand the challe
Development of an ELISA for the quantification of mycolactone, the cytotoxic macrolide toxin of <em>Mycobacterium ulcerans</em> (Publications)
Mycolactones, macrolide cytotoxins, are key virulence factors of Mycobacterium ulcerans, the etiological agent of the chronic necrotizing skin disease Buruli ulcer. There is urgent need for a simple p
Evaluation of different methods and data sources to optimise modelling of NO2 at a global scale (Publications)
BACKGROUND: In countries where air pollution stations are unavailable or scarce, station measurements from other countries and atmospheric remote sensing could jointly provide information to estimate
