Discovery and structure-activity relationships of quinazolinone-2-carboxamide derivatives as novel orally efficacious antimalarials (Publications)
A phenotypic high-throughput screen allowed discovery of quinazolinone-2-carboxamide derivatives as a novel antimalarial scaffold. Structure-activity relationship studies led to identification of a po
The effect of exposure to radiofrequency fields on cancer risk in the general and working population: a protocol for a systematic review of human... (Publications)
BACKGROUND: The World Health Organization (WHO) has an ongoing project to assess potential health effects of exposure to radiofrequency electromagnetic fields (RF-EMF) in the general and working popul
Access to water and sanitation infrastructures for primary schoolchildren in the south-central part of Côte d’Ivoire (Publications)
In rural settings of Côte d’Ivoire, access to water, sanitation, and hygiene (WASH) at schools is often lacking. The purpose of this study was to assess the availability, quality, and use of WASH infr
Identification of the asymptomatic <em>Plasmodium falciparum</em> and <em>Plasmodium vivax</em> gametocyte reservoir under different transmission... (Publications)
BACKGROUND: Understanding epidemiological variables affecting gametocyte carriage and density is essential to design interventions that most effectively reduce malaria human-to-mosquito transmission.
Implementation of a non-communicable disease clinic in rural Sierra Leone: early experiences and lessons learned (Publications)
This study is an evaluation of the first cohort of patients enrolled in an outpatient non-communicable disease clinic in Kono, Sierra Leone. In the first year, the clinic enrolled 916 patients. Eight
Mutasynthesis of physostigmines in <em>Myxococcus xanthus</em> (Publications)
The alkaloid physostigmine is an approved anticholinergic drug and an important lead structure for the development of novel therapeutics. Using a complementary approach that merged chemical synthesis
A health systems resilience research agenda: moving from concept to practice (Publications)
Health system resilience, known as the ability for health systems to absorb, adapt or transform to maintain essential functions when stressed or shocked, has quickly gained popularity following shocks
Dynamics of the COVID-19 epidemic in Ireland under mitigation (Publications)
BACKGROUND: In Ireland and across the European Union the COVID-19 epidemic waves, driven mainly by the emergence of new variants of the SARS-CoV-2 have continued their course, despite various interven