Association between advanced glycation end products and impaired fasting glucose: results from the SALIA study (Publications)
Advanced glycation end products (AGEs) may contribute to the development of type 2 diabetes and related complications, whereas their role in the early deterioration of glycaemia is unknown. While prev
The integrated disease surveillance and response system in northern Ghana: challenges to the core and support functions (Publications)
BACKGROUND: The integrated disease surveillance and response (IDSR) strategy was adopted in Ghana over a decade ago, yet gaps still remain in its proper functioning. The objective of this study was to
AMBITION-cm: intermittent high dose AmBisome on a high dose fluconazole backbone for cryptococcal meningitis induction therapy in sub-Saharan Africa:... (Publications)
BACKGROUND: Cryptococcal meningitis (CM) is a leading cause of mortality among HIV-infected individuals in Africa. Poor outcomes from conventional antifungal therapies, unavailability of flucytosine,
Repurposing of anticancer drugs: <em>in vitro</em> and<em> in vivo</em> activities against <em>Schistosoma mansoni</em> (Publications)
BACKGROUND: Drug discovery for the neglected tropical disease schistosomiasis has a high priority. Anticancer drugs, especially protein kinase inhibitors, might serve as a starting point for drug disc
Maturation and mip-1beta production of cytomegalovirus-specific T cell responses in Tanzanian children, adolescents and adults: impact by HIV and... (Publications)
It is well accepted that aging and HIV infection are associated with quantitative and functional changes of CMV-specific T cell responses. We studied here the expression of Mip-1beta and the T cell ma
Osteopathology and selenium deficiency co-occurring in a population of endangered Patagonian huemul (<em>Hippocamelus bisulcus</em>) (Publications)
BACKGROUND: About 1,000 endangered Patagonian huemul deer (Hippocamelus bisulcus) remain in Chile and 350-500 in Argentina. Most groups (> 100) are not recovering, and prevalence of osteopathology in
Do holes in long-lasting insecticidal nets compromise their efficacy against pyrethroid resistant <em>Anopheles gambiae</em> and <em>Culex... (Publications)
BACKGROUND: Resistance of malaria vectors to pyrethroids threatens the effectiveness of long-lasting insecticidal nets (LLINs) as a tool for malaria control. Recent experimental hut and observational