Transition bias influences the evolution of antibiotic resistance in <em>Mycobacterium tuberculosis</em> (Publications)
Transition bias, an overabundance of transitions relative to transversions, has been widely reported among studies of the rates and spectra of spontaneous mutations. However, demonstrating the role of
The impact of using primaquine without prior G6PD testing: a case series describing the obstacles to the medical management of haemolysis (Publications)
Radical cure of Plasmodium vivax malaria in glucose-6-phosphate dehydrogenase (G6PD) deficient individuals employs weekly primaquine dosing. This is the only recommended regimen for this patient sub-g
Evaluation of emodepside in laboratory models of human intestinal nematode and schistosome infections (Publications)
BACKGROUND: Helminthiases are very prevalent worldwide, yet their treatment and control rely on a handful of drugs. Emodepside, a marketed broad-spectrum veterinary anthelminthic with a unique mechani
The mediating effect of immune markers on the association between ambient air pollution and adult-onset asthma (Publications)
We aim to investigate to what extent a set of immune markers mediate the association between air pollution and adult-onset asthma. We considered long-term exposure to multiple air pollution markers an
An unusually broad series of seven cyclombandakamines, bridged dimeric naphthylisoquinoline alkaloids from the Congolese liana <em>Ancistrocladus... (Publications)
A series of seven unusual dimeric naphthylisoquinoline alkaloids was isolated from the leaves of the tropical liana Ancistrocladus ealaensis J. Leonard, named cyclombandakamine A (1), 1-epi-cyclomband
Persistent hot spots in Schistosomiasis Consortium for Operational Research and Evaluation studies for gaining and sustaining control of... (Publications)
Control of schistosomiasis presently relies largely on preventive chemotherapy with praziquantel through mass drug administration (MDA) programs. The Schistosomiasis Consortium for Operational Researc
