Using yeast synthetic lethality to inform drug combination for malaria (Publications)
Combinatorial chemotherapy is necessary for the treatment of malaria. However, finding a suitable partner drug for a new candidate is challenging. Here we develop an algorithm that identifies all of t
Orientia <em>tsutsugamushi</em> is highly susceptible to the RNA polymerase switch region inhibitor corallopyronin a <em>in vitro</em> and<em> in... (Publications)
Scrub typhus is a potentially lethal infection caused by the obligate intracellular bacterium Orientia tsutsugamushi Reports on the emergence of doxycycline-resistant strains highlight the urgent need
The effect of case management and vector-control interventions on space-time patterns of malaria incidence in Uganda (Publications)
BACKGROUND: Electronic reporting of routine health facility data in Uganda began with the adoption of the District Health Information Software System version 2 (DHIS2) in 2011. This has improved healt
Are public-private partnerships the solution to tackle neglected tropical diseases? A systematic review of the literature (Publications)
Pharmaceutical companies are reluctant to invest in research and development (R&D) of products for neglected tropical diseases (NTDs) mainly due to the low ability-to-pay of health insurance systems a
Occupational exposures and 20-year incidence of COPD: the European Community Respiratory Health Survey (Publications)
BACKGROUND: Occupational exposures have been associated with an increased risk of COPD. However, few studies have related objectively assessed occupational exposures to prospectively assessed incidenc