Integral solvent-induced protein precipitation for target-engagement studies in <em>Plasmodium falciparum</em> (Publications)
The limited understanding of the mechanism of action (MoA) of several antimalarials and the rise of drug resistance toward existing malaria therapies emphasizes the need for new strategies to uncover
Characterizing the pharmacological interaction of the antimalarial combination artefenomel-piperaquine in healthy volunteers with induced blood-stage... (Publications)
BACKGROUND: The combination antimalarial artefenomel-piperaquine failed to achieve target efficacy in a phase 2b study in Africa and Vietnam. We retrospectively evaluated whether characterizing the ph
Considerations and expectations for the administration of dispersible arpraziquantel to young children: a landscape analysis (Publications)
Schistosomiasis is a serious public health problem in many African countries and beyond. Preventive chemotherapy with praziquantel is a successful public health intervention that is recommended for al
Ensuring Africa's food security by 2050: the role of population growth, climate-resilient strategies, and putative pathways to resilience (Publications)
Africa is grappling with severe food security challenges driven by population growth, climate change, land degradation, water scarcity, and socio-economic factors such as poverty and inequality. Clima
The interspecific competition between larvae of <em>Aedes aegypti</em> and major african malaria vectors in a semi-field system in Tanzania (Publications)
Interspecific competition between mosquito larvae may affects adult vectorial capacity, potentially reducing disease transmission. It also influences population dynamics, and cannibalistic and predato
