Methods for diagnosing proteinuria: when to use which test, and why (Publications)
of the methodology is crucial for the interpretation of the results. In addition to the distinction between semi-quantitative and quantitative tests, there are also relevant differences within the two [...] ii) a lack of specificity regarding the type of proteinuria, iii) a high rate of false positive tests with the need for re-testing with a quantitative method for verification. In contrast, quantitative [...] review, the different types of tests for proteinuria, their underlying methodologies...
A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order (Publications)
seasonal allergic rhinitis (AR) is a chronic disorder associated with IgE sensitization to grass. The underlying genetic variants have not been studied comprehensively. There is overwhelming evidence that those [...] 032 control subjects). RESULTS: Three loci reached genome-wide significance for either phenotype. The HLA variant rs7775228, which cis-regulates HLA-DRB4, was strongly associated with grass sensitization [...] ng oligomerization domain containing 1 (NOD1/CARD4). We found no evidence...
A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order (Publications)
seasonal allergic rhinitis (AR) is a chronic disorder associated with IgE sensitization to grass. The underlying genetic variants have not been studied comprehensively. There is overwhelming evidence that those [...] 032 control subjects). RESULTS: Three loci reached genome-wide significance for either phenotype. The HLA variant rs7775228, which cis-regulates HLA-DRB4, was strongly associated with grass sensitization [...] ng oligomerization domain containing 1 (NOD1/CARD4). We found no evidence...
Gender differences in disordered eating and weight dissatisfaction in Swiss adults: which factors matter? (Publications)
disordered eating across the adult life span are still limited. Gender is a significant factor in relation to weight dissatisfaction and disordered eating. However, the reasons for gender differences in these [...] disordered eating across the adult life span are still limited. Gender is a significant factor in relation to weight dissatisfaction and disordered eating. However, the reasons for gender differences in these [...] disordered eating across the adult life span are still limited. Gender...
Gender differences in disordered eating and weight dissatisfaction in Swiss adults: which factors matter? (Publications)
disordered eating across the adult life span are still limited. Gender is a significant factor in relation to weight dissatisfaction and disordered eating. However, the reasons for gender differences in these [...] disordered eating across the adult life span are still limited. Gender is a significant factor in relation to weight dissatisfaction and disordered eating. However, the reasons for gender differences in these [...] disordered eating across the adult life span are still limited. Gender...
Estimation of infection and recovery rates for highly polymorphic parasites when detectability is imperfect, using hidden Markov models (Publications)
presence of the parasite, which evolves according to a first-order Markov chain. The model allows the transition probabilities of the hidden states as well as the detectability parameter of the test to depend [...] Markov process, where the observed process is the detection or failure to detect a parasitic genotype. This is assumed to be conditionally independent given the hidden process, that is, the underlying true presence [...] hierarchical model is proposed for estimating parasitic...
Estimation of infection and recovery rates for highly polymorphic parasites when detectability is imperfect, using hidden Markov models (Publications)
presence of the parasite, which evolves according to a first-order Markov chain. The model allows the transition probabilities of the hidden states as well as the detectability parameter of the test to depend [...] Markov process, where the observed process is the detection or failure to detect a parasitic genotype. This is assumed to be conditionally independent given the hidden process, that is, the underlying true presence [...] hierarchical model is proposed for estimating parasitic...
The extended AT-hook is a novel RNA binding motif (Publications)
describe the discovery and characterization of the extended AT-hook peptide motif (eAT-hook), in which basic amino acids appear symmetrical mainly at a distance of 12-15 amino acids from the G-R-P core [...] motif, and show that eAT-hooks bind RNA with one order of magnitude higher affinity than DNA. In addition, cellular localization studies suggest a role for the N-terminal eAT-hook of PTOV1 in nucleocytoplasmic [...] The AT-hook has been defined as a DNA binding peptide motif that contains a...
The extended AT-hook is a novel RNA binding motif (Publications)
describe the discovery and characterization of the extended AT-hook peptide motif (eAT-hook), in which basic amino acids appear symmetrical mainly at a distance of 12-15 amino acids from the G-R-P core [...] motif, and show that eAT-hooks bind RNA with one order of magnitude higher affinity than DNA. In addition, cellular localization studies suggest a role for the N-terminal eAT-hook of PTOV1 in nucleocytoplasmic [...] The AT-hook has been defined as a DNA binding peptide motif that contains a...
<em>“It is like we are living in a different world”</em>: health inequity in communities surrounding industrial mining sites in Burkina Faso,... (Publications)
prominently in the 2030 Agenda for Sustainable Development, yet there are wide disparities in health between and within countries. In settings of natural resource extraction (e.g., industrial mines), the health [...] surrounding communities is affected through myriad changes in the physical, social, and economic environment. How changes triggered by such projects translate into health inequities is poorly understood. Methods: [...] widen existing health gaps. In order to create equal...
